Protein Info for IAI46_06175 in Serratia liquefaciens MT49

Annotation: potassium-transporting ATPase subunit KdpB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 689 transmembrane" amino acids 35 to 56 (22 residues), see Phobius details amino acids 62 to 82 (21 residues), see Phobius details amino acids 219 to 242 (24 residues), see Phobius details amino acids 255 to 281 (27 residues), see Phobius details amino acids 583 to 605 (23 residues), see Phobius details amino acids 620 to 641 (22 residues), see Phobius details amino acids 661 to 687 (27 residues), see Phobius details TIGR01497: K+-transporting ATPase, B subunit" amino acids 3 to 682 (680 residues), 1167.6 bits, see alignment E=0 TIGR01494: HAD ATPase, P-type, family IC" amino acids 72 to 349 (278 residues), 121.2 bits, see alignment E=4e-39 amino acids 379 to 610 (232 residues), 160.4 bits, see alignment E=5.5e-51 PF00122: E1-E2_ATPase" amino acids 112 to 288 (177 residues), 110.7 bits, see alignment E=9.2e-36 PF00702: Hydrolase" amino acids 307 to 536 (230 residues), 96.1 bits, see alignment E=5.4e-31

Best Hits

Swiss-Prot: 83% identical to KDPB_PHOLL: Potassium-transporting ATPase ATP-binding subunit (kdpB) from Photorhabdus luminescens subsp. laumondii (strain DSM 15139 / CIP 105565 / TT01)

KEGG orthology group: K01547, K+-transporting ATPase ATPase B chain [EC: 3.6.3.12] (inferred from 86% identity to dze:Dd1591_2928)

MetaCyc: 82% identical to K+ transporting P-type ATPase subunit KdpB (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-2 [EC: 7.2.2.6]

Predicted SEED Role

"Potassium-transporting ATPase B chain (EC 3.6.3.12) (TC 3.A.3.7.1)" in subsystem Potassium homeostasis (EC 3.6.3.12, TC 3.A.3.7.1)

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.12

Use Curated BLAST to search for 3.6.3.12 or 7.2.2.6

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (689 amino acids)

>IAI46_06175 potassium-transporting ATPase subunit KdpB (Serratia liquefaciens MT49)
MTRKQRALFEPALVRTALIDALKKLDPRTQWRNPVMFVVYIGSILTTAIWLAILAGQTDG
SAAFTGSIALWLWFTVLFANFAEALAEGRSKAQAESLRGTKKTSWAKKLAAPRRDGATEK
VSAESLRKGDIVLVEAGDTIPCDGEVLEGGASVDESAITGESAPVIRESGGDFSSVTGGT
RVLSDWLVVQCSVNPGETFLDRMIAMVEGAKRRKTPNEVALTILLVALTIVFVLATATLF
PFSQYSVDAANGGSVVTITVLVALLVCLIPTTIGGLLSAIGVAGMSRMLGANVIATSGRA
VEAAGDVDVLLLDKTGTITLGNRQASEFLPAPGVKEQDLADAAQLSSLADETPEGRSIVV
LAKQRFNLRERDLQALNATFVPFSAQTRMSGVNVQDRMIRKGAVDAIRRHVESNQGHFPQ
AVDELVASVARTGGTPLVVAEGPRVLGVVALKDIVKGGIKERFAELRKMGIKTVMITGDN
PLTAAAIAAEAGVDDFLSEATPEAKLALIRQYQAEGRLVAMTGDGTNDAPALAQADVAVA
MNSGTQAAKEAGNMVDLDSNPTKLIEVVHIGKQMLMTRGSLTTFSIANDVAKYFAIIPAA
FAATYPQLNALNVMHLHSPASAIMSAVIFNALVIVFLIPLALKGVSYKPMSAAALLRRNL
WLYGVGGLLVPFVGIKLIDLILVALHIAG