Protein Info for IAI46_06115 in Serratia liquefaciens MT49

Annotation: carbohydate-binding domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 885 signal peptide" amino acids 1 to 28 (28 residues), see Phobius details PF03173: CHB_HEX" amino acids 37 to 195 (159 residues), 215.8 bits, see alignment E=5.4e-68 PF02838: Glyco_hydro_20b" amino acids 216 to 335 (120 residues), 64.8 bits, see alignment E=2.6e-21 PF00728: Glyco_hydro_20" amino acids 339 to 765 (427 residues), 323.7 bits, see alignment E=3.4e-100 PF03174: CHB_HEX_C" amino acids 806 to 882 (77 residues), 103.3 bits, see alignment E=1.1e-33

Best Hits

Swiss-Prot: 86% identical to CHB_SERMA: Chitobiase (chb) from Serratia marcescens

KEGG orthology group: K12373, hexosaminidase [EC: 3.2.1.52] (inferred from 94% identity to spe:Spro_1232)

MetaCyc: 86% identical to chitobiase (Serratia marcescens)
Beta-N-acetylhexosaminidase. [EC: 3.2.1.52]

Predicted SEED Role

"Beta-hexosaminidase (EC 3.2.1.52)" in subsystem Chitin and N-acetylglucosamine utilization or N-Acetyl-Galactosamine and Galactosamine Utilization (EC 3.2.1.52)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.2.1.52

Use Curated BLAST to search for 3.2.1.52

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (885 amino acids)

>IAI46_06115 carbohydate-binding domain-containing protein (Serratia liquefaciens MT49)
MNKFKLSALAALTATIGLFGSVGNAMANQPLVDQLSQLKLNLKMVDNRAAENGLDCGKLG
ADWAACNKVLIGLTNDNQEINGQDWAIYFHSARQTLRVDNDQFKISHLTGDLYKLEPTDK
FTGFPAGKTVEIPIITEYWQLFKTDFVPRWYATSGDAKPKILVNTDTEDLNQFVAPFTGD
QWKRTKDDNNILMTPASRFTKNAELKTLPTTSLRGQIVPTPLQVKVHAQDVDLSKGVALE
LSALSKPAADAVAQRFALLGITSNAAGYPIKTDIQPGIFKGELAVPGAYELIIGKQEARV
IGFDQTGVFYGLQSILSLVPTEGSAKIATLEAKDAPRLQYRGIFLDVARNFHQKDAVLRL
LDQMAAYKLNKFHFHLSDDEGWRIAIPGLPELTEVGGQRCHDLSETTCLLPQYGQGPEVY
GGFFSRQDYIDIIKYAKARQIEVIPEIDMPAHARAAVVSMEARYKKLHAAGKEQEANEFR
LVDPTDTSNTTSVQYFNRQSYLNPCLDSSKRFVDKVIGEIAQMHKEAGQPLSTWHFGGDE
AKNIRLGAGYTDVNKPEAGKGIIDQSKEDKPWAKSQVCQAMIKDGKVADMEHLPSYFGVE
VSQLVKAHGIDRMQAWQDGLKDAKNAKAFATQRVGVNFWDTLYWGGFDSANDWANKGYEL
ILSNPDYVYMDFPYEVNPDERGYYWGTRFSDEQKMFSFAPNNLPQNAETSVDRDGNHFTA
KSDKPWPGAYGISAQMWSETQRTDEQMEYMIFPRSLSVAERAWHRAEWEQDYRAGREYKG
GETHFIDTKKLDRDWLRFANLLGQRELAKLDKGGVNYRLPVPGARVVGGKLEANISLPGL
GIEYSTDGGKQWQRYDAKAKPGVSGEVQIRAVSPDGKRYSRAEKV