Protein Info for IAI46_05990 in Serratia liquefaciens MT49

Annotation: amino acid ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 246 transmembrane" amino acids 25 to 52 (28 residues), see Phobius details amino acids 68 to 88 (21 residues), see Phobius details amino acids 108 to 127 (20 residues), see Phobius details amino acids 184 to 192 (9 residues), see Phobius details amino acids 211 to 231 (21 residues), see Phobius details TIGR01726: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family" amino acids 24 to 132 (109 residues), 55.1 bits, see alignment E=4.5e-19 PF00528: BPD_transp_1" amino acids 46 to 237 (192 residues), 89.4 bits, see alignment E=1.3e-29

Best Hits

Swiss-Prot: 90% identical to GLTJ_ECOLI: Glutamate/aspartate import permease protein GltJ (gltJ) from Escherichia coli (strain K12)

KEGG orthology group: K10003, glutamate/aspartate transport system permease protein (inferred from 100% identity to spe:Spro_1213)

MetaCyc: 90% identical to glutamate/aspartate ABC transporter membrane subunit GltJ (Escherichia coli K-12 substr. MG1655)
ABC-13-RXN [EC: 7.4.2.1]; 7.4.2.1 [EC: 7.4.2.1]

Predicted SEED Role

"Glutamate Aspartate transport system permease protein GltJ (TC 3.A.1.3.4)" (TC 3.A.1.3.4)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.4.2.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (246 amino acids)

>IAI46_05990 amino acid ABC transporter permease (Serratia liquefaciens MT49)
MSIDWNWGIFLQQAPFGNTTYLGWIWSGFQVTVALSVCAWIIAFFVGSLFGILRTVPNRF
LSTLGTCYVELFRNVPLIVQFFTWYLVIPELLPANIGMWFKTELDPNVQFFVSSMLCLGL
FTAARVCEQVRAAIQSLPRGQRAAGLAMGLTLPQTYRYVLLPNAYRVIVPPMTSEMLNLV
KNSAIASTIGLVDMAAQAGKLLDYSAHAYESFTAITLAYIAINAVIMLFMRLVERKVQLP
GNLGSK