Protein Info for IAI46_05925 in Serratia liquefaciens MT49

Annotation: peptidoglycan glycosyltransferase MrdB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 370 transmembrane" amino acids 20 to 38 (19 residues), see Phobius details amino acids 50 to 68 (19 residues), see Phobius details amino acids 74 to 93 (20 residues), see Phobius details amino acids 136 to 154 (19 residues), see Phobius details amino acids 160 to 177 (18 residues), see Phobius details amino acids 183 to 205 (23 residues), see Phobius details amino acids 264 to 289 (26 residues), see Phobius details amino acids 306 to 332 (27 residues), see Phobius details amino acids 338 to 359 (22 residues), see Phobius details TIGR02210: rod shape-determining protein RodA" amino acids 17 to 364 (348 residues), 453.2 bits, see alignment E=3.2e-140 PF01098: FTSW_RODA_SPOVE" amino acids 21 to 364 (344 residues), 417.1 bits, see alignment E=2.9e-129

Best Hits

Swiss-Prot: 86% identical to RODA_ECO57: Peptidoglycan glycosyltransferase MrdB (mrdB) from Escherichia coli O157:H7

KEGG orthology group: K05837, rod shape determining protein RodA (inferred from 100% identity to spe:Spro_1200)

MetaCyc: 86% identical to peptidoglycan glycosyltransferase MrdB (Escherichia coli K-12 substr. MG1655)
Peptidoglycan glycosyltransferase. [EC: 2.4.1.129]

Predicted SEED Role

"Rod shape-determining protein RodA" in subsystem Bacterial Cytoskeleton or Peptidoglycan Biosynthesis

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.4.1.129

Use Curated BLAST to search for 2.4.1.129

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (370 amino acids)

>IAI46_05925 peptidoglycan glycosyltransferase MrdB (Serratia liquefaciens MT49)
MTESQQKASIWTKIHIDPTFLLLILALLVYSAFVMWSASGQDIGMMERKIGQIVMGLIVM
AVMAQIPPRVYESWAPYLYIFCVILLILVDAFGQISKGAQRWLDLGFVRFQPSEIAKIAV
PLMVARFMNRDVCPPSLKNTAIALVLIFLPTLLVAAQPDLGTSILIAASGLFVLFLSGMS
WKLIAVAAVLLAAFIPVLWFFLMHGYQRDRVMMLLDPETDPLGAGYHIIQSKIAIGSGGL
SGKGWLHGTQSQLEFLPERHTDFIFAVLAEELGLVGVLVLLALYLLVIIRGLMIAAKAQT
TFGRVMVGGLMLILFVYVFVNIGMVSGILPVVGVPLPLVSYGGSALIVLMAGFGIIMSIH
THRKMMSKSL