Protein Info for IAI46_05730 in Serratia liquefaciens MT49

Annotation: zinc-dependent alcohol dehydrogenase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 329 PF08240: ADH_N" amino acids 29 to 92 (64 residues), 35 bits, see alignment E=1.7e-12 PF00107: ADH_zinc_N" amino acids 158 to 272 (115 residues), 90.7 bits, see alignment E=1.2e-29 PF13602: ADH_zinc_N_2" amino acids 190 to 327 (138 residues), 58.3 bits, see alignment E=2.7e-19

Best Hits

KEGG orthology group: None (inferred from 54% identity to mex:Mext_2454)

Predicted SEED Role

"Quinone oxidoreductase (EC 1.6.5.5)" in subsystem ZZ gjo need homes (EC 1.6.5.5)

Isozymes

Compare fitness of predicted isozymes for: 1.6.5.5

Use Curated BLAST to search for 1.6.5.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (329 amino acids)

>IAI46_05730 zinc-dependent alcohol dehydrogenase family protein (Serratia liquefaciens MT49)
MARVIQFDRVGEPDVLKIVDVALPALAADEVSIKVKAIGLNRAEALLRRGKYAFPPVFPQ
RMGYEAAGIIEAVGAQVQGLIPGDAVSVIPSLAMDRWPTYGETIHYPARYVVKHPENLSW
EQAASAWMQYITAYGALIDVAEVTSDDYVMVTAASSSVGIAAIQIANMLGARVIATSRTE
SKRQALLDIGASWVVTSQGEKSVAEVKEITGDRPPRVIFDCIGGEGVPTLCEILAPGGTL
IEYGNLSGENTPFPASLAIPKGLTIRGFAYSEIVGNAARLANAKTFILAALSRGELKPVI
AKSFVFDQIVAAHQYLEANAQLGKIVVTV