Protein Info for IAI46_05325 in Serratia liquefaciens MT49

Annotation: SPFH/Band 7/PHB domain protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 301 signal peptide" amino acids 1 to 19 (19 residues), see Phobius details PF01145: Band_7" amino acids 21 to 191 (171 residues), 133.6 bits, see alignment E=3.9e-43

Best Hits

Swiss-Prot: 85% identical to QMCA_SHIFL: Protein QmcA (qmcA) from Shigella flexneri

KEGG orthology group: None (inferred from 99% identity to srr:SerAS9_1082)

Predicted SEED Role

"Putative stomatin/prohibitin-family membrane protease subunit YbbK" in subsystem YbbK

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (301 amino acids)

>IAI46_05325 SPFH/Band 7/PHB domain protein (Serratia liquefaciens MT49)
MFTLIPIVIVVALIIVFAGVKIVPQGFQWTVERFGRYTKTLMPGLNLVVPFMDRIGRKIN
MMEQVLDIPSQEIISRDNANVAIDAVCFIQVVDPARAAYEVSNLELAIVNLTMTNFRTVL
GSMELDEILSQRDSINSRLLHIVDEATNPWGIKITRIEIRDVRPPAELISAMNAQMKAER
TKRADILEAEGVRQAAILRAEGDKQSQILKAEGERQSAFLQAEARERAAEAEARATQLVS
DAIASGNIQAVNYFVAQKYTDALQKIGSANNSKVIMMPLDASSLLGSIGGIAELLKDTKG
K