Protein Info for IAI46_04790 in Serratia liquefaciens MT49
Annotation: cobalamin-independent methionine synthase II family protein
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 60% identical to YXJH_BACSU: Uncharacterized protein YxjH (yxjH) from Bacillus subtilis (strain 168)
KEGG orthology group: None (inferred from 95% identity to srr:SerAS9_0969)Predicted SEED Role
"Methionine synthase II (cobalamin-independent)"
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (368 amino acids)
>IAI46_04790 cobalamin-independent methionine synthase II family protein (Serratia liquefaciens MT49) MCDCNSAFHADVVGSLLRPAALKTARQQFLQGEIDALQLREVEDQQIRLAVAKQKDLGLA VVTDGEFRRAWWHFDFLEGLDGVEGYDAEQGIQFNGVQTRARSIKVVGKLGFNPQHPMLE DFRFLKAIAGDAVPKMTIPSPSVLHFRGGRKAIDSQVYPDLNAYFDDLAQTYREAIKAFY DAGCRYLQLDDTVWAYLCSDDQRRQIRERGEDPDLLARIYADVLNAAIADKPEDLIIGLH VCRGNFRSTWISEGGYEPVAEILFGQVNIDAFFLEYDNERSGGFEPLRFIKPGKQQVVLG LITTKNGELENPEQVKQRLEEAAQFVDRRQLCLSTQCGFASTEEGNSLSEQQQWNKLQSV VNIAEQVW