Protein Info for IAI46_04645 in Serratia liquefaciens MT49

Annotation: TonB-dependent siderophore receptor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 709 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details PF07715: Plug" amino acids 67 to 163 (97 residues), 74.1 bits, see alignment E=1.3e-24 TIGR01783: TonB-dependent siderophore receptor" amino acids 68 to 709 (642 residues), 354.9 bits, see alignment E=5e-110 PF00593: TonB_dep_Rec" amino acids 236 to 678 (443 residues), 218.1 bits, see alignment E=4.4e-68

Best Hits

KEGG orthology group: K02014, iron complex outermembrane recepter protein (inferred from 96% identity to spe:Spro_1016)

Predicted SEED Role

"Ferrichrome-iron receptor" in subsystem Iron acquisition in Vibrio or Transport of Iron

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (709 amino acids)

>IAI46_04645 TonB-dependent siderophore receptor (Serratia liquefaciens MT49)
MNNTQRGWWCALPLAACASAPAIGADKTAEKEPGETLVVVGQASAKGVQSYQPLTSVTGT
RTETSLLNVPQAIDVVPQQVITDQAVSSLDEALYNVSGITQANTLGGTQDAVMKRGFGDN
RDGSILRDGVRSVQARNFTPTTERVEVLKGPASMLYGMGEPGGMINMITKKPQLQQRTHV
EGWGSSFKGGGGQLDVTGPLGTSGFAYRMIVDHDETDYWRNFGRNRQTVIAPSLMWYGES
TTVRVAYEHMEYLVPFDRGTIIDSRTGKPVNTPRDRRFDESYNATRGDQDSVTLQVDQVL
NESWKSSLTYAYSRNSYSDNQARALALDPETGVLSRQADSTAHAVSHANAVQLTLNGDVD
WGSINHQMLFGFDFEDNRTYRGDMIRGKKNSDFNIYDPVYGLMPTSNAVSAKDSDQRENL
TSYGWFMQDSVQLTDKWLVMGGLRYDAFDVFAGKGRPFVTNTDSSDGKLVPRAGVVYKLT
PYVSLYSSYTESFKPNSSIASQIGSLPPEQGKAWEVGSKVELPNGVTGTLALFDITKRNV
MVSELVDGETVTRTAGRVRSQGVELDVAGNITDSLSMIGSYAYTDARVVDDPDNKGKEMT
NVARHTASLFLTQDLGSPGLYSGDNVRIGAGARYVGRRPGDAANSFSLDNYTVADAFAAY
TMPVQGYRVKWQLNVKNLFDKTYYPSSGGNLRVAVGEPREVVLRASVDF