Protein Info for IAI46_04180 in Serratia liquefaciens MT49

Annotation: TonB-dependent siderophore receptor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 744 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details PF07715: Plug" amino acids 44 to 145 (102 residues), 70.8 bits, see alignment E=1.3e-23 TIGR01783: TonB-dependent siderophore receptor" amino acids 45 to 744 (700 residues), 451.1 bits, see alignment E=3.9e-139 PF00593: TonB_dep_Rec" amino acids 236 to 700 (465 residues), 116.5 bits, see alignment E=2.9e-37

Best Hits

Swiss-Prot: 68% identical to IUTA_KLEPN: Ferric aerobactin receptor (iutA) from Klebsiella pneumoniae

KEGG orthology group: None (inferred from 96% identity to spe:Spro_0918)

Predicted SEED Role

"Aerobactin siderophore receptor IutA @ TonB-dependent siderophore receptor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (744 amino acids)

>IAI46_04180 TonB-dependent siderophore receptor (Serratia liquefaciens MT49)
MKRKHLWVLNPCLLAMLAPTAWAEEQKSEEQMVVSASRTHRTVAEMAQTTWVIESQEIEQ
QVQGGKEIKDMLAQLIPGMDVSGQGRTNYGMNLRGRSMMVMIDGVRLNSSRSDSRQLDSI
DPFNIDHIEVISGATSLYGGGSTGGLINIVTKKGQKEQQVELQIGGKTGFGGHTDHDENV
AAAVSGGNDNASGRLSVSYQRYGGWYDGKGNEVLIDNTQTGLQYSDRLDVMGTGTINIDD
HQQLQLTTQYYKSQSDGDHGLFLGENFAAVTGSAKAYNSGNLNSDRIPGTERHLINLQYS
NTDFLGQDLVAQVYYRDESLTFYPFPTLAGKAPNYYVSSIGASQQKTDFYGGKLTLNSKP
IEALTLTYGIDAEHETFNSNQQFFDLAKAQQSGGMDLQNAYNTGRYPGYSTTNLASFLQA
SYDINPIFTLSGGVRYQYTENKIDDFVGYNQQQAIATGAATSADAIPGGKTDYNNALFNA
GLLAHLTERQQTWINFSQGYEIPDPGKYYGNGTYALNNGHYQLNKSVNVGDSKLEGIKVN
SYELGWRYTGDNLRTQIAGYYSLSDKSISINKTDMTINVNSDKRRIYGMEGAVDYFFEDS
DWSAGTNFNFIRSETKVNGEWKKLVVDTASPSKVTAYVGWAPGDWNLRLQSQQTFDVSDD
GDYTKAGSTQGRKIDGYNTIDFLGSYALPVGKLSFSVENLLDKEYTTVWGQRAPILYSPT
YGSPELYSYKGRGRTFGLNYSVLF