Protein Info for IAI46_04125 in Serratia liquefaciens MT49

Annotation: endonuclease/exonuclease/phosphatase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 264 transmembrane" amino acids 137 to 149 (13 residues), see Phobius details PF03372: Exo_endo_phos" amino acids 43 to 248 (206 residues), 50.1 bits, see alignment E=1.6e-17

Best Hits

Swiss-Prot: 79% identical to YAFD_SHIFL: UPF0294 protein YafD (yafD) from Shigella flexneri

KEGG orthology group: None (inferred from 98% identity to srs:SerAS12_0831)

Predicted SEED Role

"FIG01055581: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (264 amino acids)

>IAI46_04125 endonuclease/exonuclease/phosphatase family protein (Serratia liquefaciens MT49)
MPKRTYAMRYVAGQPVERIFPGAINQPLPPGAALPTSGALRVMVWNIFKQQRADWLSVLK
SYGKDAQLVLLQEAQTTPELVSFATSNYLAADQVPAFVLPQHPSGVMTLAAAHPVYCCPL
REREPLLRLAKSALITVYPLFNGQLLMVVNIHAVNFSLGVDVYSKQLGPIGEQIANHHGP
VIMAGDFNAWSRKRINALYQFASDMALREVNFTDDHRRKAFGRPLDFVFYRNMGVAEASV
LVTSASDHNPLLVEFHPEADKPHW