Protein Info for IAI46_03905 in Serratia liquefaciens MT49

Annotation: HlyC/CorC family transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 429 transmembrane" amino acids 6 to 25 (20 residues), see Phobius details amino acids 62 to 86 (25 residues), see Phobius details amino acids 92 to 113 (22 residues), see Phobius details amino acids 138 to 158 (21 residues), see Phobius details PF01595: CNNM" amino acids 11 to 184 (174 residues), 188.8 bits, see alignment E=1e-59 PF00571: CBS" amino acids 278 to 326 (49 residues), 27.3 bits, see alignment 5.5e-10 PF03471: CorC_HlyC" amino acids 344 to 419 (76 residues), 75.4 bits, see alignment E=4.3e-25

Best Hits

Swiss-Prot: 80% identical to YFJD_ECOLI: UPF0053 inner membrane protein YfjD (yfjD) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 97% identity to spe:Spro_0849)

Predicted SEED Role

"Magnesium and cobalt efflux protein CorC" in subsystem Copper homeostasis: copper tolerance or Phosphate metabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (429 amino acids)

>IAI46_03905 HlyC/CorC family transporter (Serratia liquefaciens MT49)
MEHVSTGTLIIILVVMIVVSAYFSASETGMMTLNRYRLRHLSKQGNRSARRVEKLLQKPD
RLIGLVLIGNNLVNILASALATIVGMRLYGDLGVAIATGVLTFAVLLFAEVLPKTFAALY
PERIAFPSSFLLAPLQKVMFPLVWLLNGITTLILRLFGIRTNVRISDAVSKDELRTIVKE
SHSQISRRNQDMLISVLDLEKVTVDDIMVPRNEIVGIDVNDDWKSIMRQLTHSPHGRIVL
YRTSLDDAIGMLRVREAYRLMTEKKEFNKENLLRAADEIYYVPEGTPLNVQLVKFQRNKE
KVGIVVDEYGDIQGLVTVEDILEEIVGDFTTSMSPTLAEEVNPQSDGSVLIDGTANVREL
NKAFNWTLPATDARTINGMLLEELEEIPEVGTRVRIGHYDISILDVQDNMIKQVRVTPIK
SLQSSVQQR