Protein Info for IAI46_02675 in Serratia liquefaciens MT49

Annotation: alpha/beta hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 268 PF12146: Hydrolase_4" amino acids 26 to 251 (226 residues), 198.8 bits, see alignment E=2.2e-62 PF12697: Abhydrolase_6" amino acids 31 to 253 (223 residues), 61.1 bits, see alignment E=6.2e-20 PF00561: Abhydrolase_1" amino acids 31 to 134 (104 residues), 74.7 bits, see alignment E=2.4e-24 PF00975: Thioesterase" amino acids 43 to 131 (89 residues), 27.8 bits, see alignment E=7e-10 PF00326: Peptidase_S9" amino acids 205 to 268 (64 residues), 24.5 bits, see alignment E=4.3e-09

Best Hits

KEGG orthology group: None (inferred from 91% identity to srs:SerAS12_0551)

Predicted SEED Role

"Monoglyceride lipase (EC 3.1.1.23)" in subsystem Cannabinoid biosynthesis or Triacylglycerol metabolism (EC 3.1.1.23)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.1.1.23

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (268 amino acids)

>IAI46_02675 alpha/beta hydrolase (Serratia liquefaciens MT49)
MSEQKISFIKGGHGDIAVHDWGHDRPRFLALLVHGYGEHLGRYQYVARTLEAQGARVFGP
DHLGHGLSQGERVLIEDYDAVVDDVRCVTEHFQRLHPGVPLVVIGHSMGGMIATRYVQRY
GDDVRALVLSGPLIGERTLISDLLTLPEIPDTPLDTATLSRDPSVGEAYQADPLVWHGPF
KRPTLRAMQQILAKINAGLGFGTLPTLWIHGDDDRLVLMAESQTAIDRLKGSDFEAMVNP
GGRHESFNETNKDQILRRITDFIERVLG