Protein Info for IAI46_02645 in Serratia liquefaciens MT49

Annotation: aspartate aminotransferase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00202: Aminotran_3
  • amino acids 31 to 442 (412 residues), 281.5 bits, E=4.8e-88

Best Hits

Swiss-Prot: 62% identical to BAUA_PSEAE: Beta-alanine--pyruvate aminotransferase (bauA) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

KEGG orthology group: K00822, beta-alanine--pyruvate transaminase [EC: 2.6.1.18] (inferred from 96% identity to spe:Spro_0607)

Predicted SEED Role

"Omega-amino acid--pyruvate aminotransferase (EC 2.6.1.18)" in subsystem Pyruvate Alanine Serine Interconversions (EC 2.6.1.18)

MetaCyc Pathways

• β-alanine degradation II (2/2 steps found)
• superpathway of coenzyme A biosynthesis II (plants) (6/10 steps found)
• β-alanine biosynthesis II (2/6 steps found)

KEGG Metabolic Maps

• Alanine and aspartate metabolism
• Propanoate metabolism
• Valine, leucine and isoleucine degradation
• beta-Alanine metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.6.1.18

Protein Sequence (446 amino acids)

>IAI46_02645 aspartate aminotransferase family protein (Serratia liquefaciens MT49)
MADLNQRENKADREWLEAHWMPFTGNRNFKANPRMISHAQGVYYTSQDGRKIFDGLSGLW
CCGLGHGRQEIADAAHRQLSRLDYSPAFQFGHALSFELANKIKAMTPAGLDYVFFTGSGS
EAADTSLKMARAYWRAKGQAGKTCFIGREKGYHGVNFGGIAVGGIAGNRKAFGASAEADH
LPHTQLAGNAFSRGMPEQGAELAEELSRIIALRDASTIAAVIVEPFSGSAGVIVPPVGYL
QRIREICTQHNILLIFDEVITAFGRCGALTGAEAFGVTPDIMNIAKQVTNGAQPMGAVVV
RPEIYQAFMATDEPEYLLEFPHGYTYSAHPVSCAVGLATLDIIEREQMIERVQALAPYFE
RAVHSLQGSNHVSDIRNFGLAAGITLAARPGEAARRPYEVAMRCWESGFYVRYGGDTLQL
APPFISSEAQIDSLINALGDAINATE