Protein Info for IAI46_02250 in Serratia liquefaciens MT49

Annotation: circularly permuted type 2 ATP-grasp protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 478 PF04174: CP_ATPgrasp_1" amino acids 78 to 407 (330 residues), 523.1 bits, see alignment E=2.7e-161 PF14403: CP_ATPgrasp_2" amino acids 78 to 451 (374 residues), 557.3 bits, see alignment E=1.6e-171

Best Hits

Swiss-Prot: 55% identical to Y335_SYNY3: Uncharacterized protein sll0335 (sll0335) from Synechocystis sp. (strain PCC 6803 / Kazusa)

KEGG orthology group: None (inferred from 100% identity to srr:SerAS9_0483)

Predicted SEED Role

"Protein containing domains DUF404, DUF407"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (478 amino acids)

>IAI46_02250 circularly permuted type 2 ATP-grasp protein (Serratia liquefaciens MT49)
MLNIDLSASPFFDEMLLAEGKHRGHYEAYWHWLQQADQKAIQRKREEAALLFHRVGITFN
VYGEDDGAERLIPFDSVPRIIPASEWAMLDRGIRQRVQALNAFLHDIYHQQHILKAGIIP
AEQVLANDQYQPCMQGVDLHRNIYAHIVGVDMVRNGDGQYYVLEDNLRTPSGVSYMLENR
KMMMRLYPELFAQQRIAPVERYPSHLLQTLRESSPINDPTVVVLTPGRFNSAYFEHSFLA
QQMGVELVESADLFVKDGAVFMRTTAGPCKVDVIYRRVDDAFLDPLAFRPDSMLGVPGLL
SVYRAGNVVLANAIGTGVADDKSIYPYVPDMVRFYLQEEPILNNVPTWQCRHKNELSYVL
ANLEQMVVKEVHGAGGYGMLIGPAATKDEIAHFRSLLLAKPHNYIAQNTLALSTCPTFVN
DGLAPRHIDLRPFALSGAEIRLVPGGLTRVALAQGSLVVNSSQGGGTKDTWVLEDDAC