Protein Info for IAI46_01855 in Serratia liquefaciens MT49

Annotation: DMT family transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 323 transmembrane" amino acids 7 to 28 (22 residues), see Phobius details amino acids 40 to 60 (21 residues), see Phobius details amino acids 73 to 93 (21 residues), see Phobius details amino acids 104 to 122 (19 residues), see Phobius details amino acids 132 to 153 (22 residues), see Phobius details amino acids 159 to 179 (21 residues), see Phobius details amino acids 189 to 207 (19 residues), see Phobius details amino acids 219 to 238 (20 residues), see Phobius details amino acids 250 to 272 (23 residues), see Phobius details amino acids 283 to 303 (21 residues), see Phobius details PF00892: EamA" amino acids 9 to 145 (137 residues), 93.2 bits, see alignment E=8.2e-31 amino acids 161 to 291 (131 residues), 58 bits, see alignment E=6.2e-20

Best Hits

Swiss-Prot: 78% identical to YHBE_SHIFL: Uncharacterized inner membrane transporter YhbE (yhbE) from Shigella flexneri

KEGG orthology group: None (inferred from 96% identity to spe:Spro_0475)

Predicted SEED Role

"Permease of the drug/metabolite transporter (DMT) superfamily" in subsystem Queuosine-Archaeosine Biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (323 amino acids)

>IAI46_01855 DMT family transporter (Serratia liquefaciens MT49)
METKQQVGIGIFLAVTTAVCWGALPIAMKEVLVVMEPFTVVWYRFTIAALGLGIILAVRG
RLPPVTMFRQPRWLLILAIATAGLLGNFIFFSSSLQYLSPTASQVIGQLSPVGMMFASVL
VLKERMRITQVIGALMLICGLLLFFNVSLIEIFTRLTDYTLGVLLGVCAAMVWVTYGVAQ
KVLLRRLASPQILVMLYTLCAIALFPLAKPEVIFQLSGWQLACLLFCGANTLIGYGALAE
AMARWQAAQVSALITLTPLFTLLFSDLLALAWPHVFAAPTLNVVGYVGAFVVVAGAMFSA
IGHRWWPRRAETRLVAPLKQPGE