Protein Info for IAI46_01675 in Serratia liquefaciens MT49

Annotation: DUF350 domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 132 transmembrane" amino acids 6 to 28 (23 residues), see Phobius details amino acids 48 to 69 (22 residues), see Phobius details amino acids 75 to 97 (23 residues), see Phobius details amino acids 109 to 128 (20 residues), see Phobius details PF03994: DUF350" amino acids 13 to 65 (53 residues), 41.2 bits, see alignment E=6.9e-15 amino acids 78 to 130 (53 residues), 51 bits, see alignment E=6e-18

Best Hits

Swiss-Prot: 58% identical to YJFL_ECOLI: UPF0719 inner membrane protein YjfL (yjfL) from Escherichia coli (strain K12)

KEGG orthology group: K08989, putative membrane protein (inferred from 97% identity to srs:SerAS12_0380)

Predicted SEED Role

"Membrane protein with DUF350 domain"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (132 amino acids)

>IAI46_01675 DUF350 domain-containing protein (Serratia liquefaciens MT49)
MDILSALAAFASYFFSGFAMVLVFLFVYTRITPHDEWALIKADNQAAAFGFVGACLGYVI
PLASAAINSVSLLDYLLWGVVALVVQLLLFAAVKIYMPRISDKIESNHVAAGIFLGGVSI
SGGVLNAACMTY