Protein Info for IAI46_01525 in Serratia liquefaciens MT49

Annotation: quaternary ammonium compound efflux SMR transporter SugE

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 105 signal peptide" amino acids 1 to 18 (18 residues), see Phobius details transmembrane" amino acids 28 to 47 (20 residues), see Phobius details amino acids 58 to 78 (21 residues), see Phobius details amino acids 84 to 102 (19 residues), see Phobius details PF00893: Multi_Drug_Res" amino acids 1 to 93 (93 residues), 108.4 bits, see alignment E=1.1e-35

Best Hits

Swiss-Prot: 79% identical to GDX_SALTI: Guanidinium exporter (gdx) from Salmonella typhi

KEGG orthology group: K11741, quaternary ammonium compound-resistance protein SugE (inferred from 94% identity to spe:Spro_0415)

MetaCyc: 79% identical to guanidinium exporter (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-368; TRANS-RXN-369

Predicted SEED Role

"Quaternary ammonium compound-resistance protein SugE"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (105 amino acids)

>IAI46_01525 quaternary ammonium compound efflux SMR transporter SugE (Serratia liquefaciens MT49)
MAWIILLIAGLLEVVWAVGLKYTHGFTRLTPSIITVAAMVVSMLLLAHAMKTLPAGTAYA
VWTGIGAVGAAIMGMVLLGESTNIARILSLCLIVVGILGLKFSSH