Protein Info for IAI46_01420 in Serratia liquefaciens MT49

Annotation: DUF2238 domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 207 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details transmembrane" amino acids 34 to 51 (18 residues), see Phobius details amino acids 60 to 81 (22 residues), see Phobius details amino acids 103 to 120 (18 residues), see Phobius details amino acids 132 to 155 (24 residues), see Phobius details amino acids 175 to 194 (20 residues), see Phobius details PF09997: DUF2238" amino acids 42 to 182 (141 residues), 184.9 bits, see alignment E=3.4e-59

Best Hits

Swiss-Prot: 71% identical to YJDF_ECOLI: Inner membrane protein YjdF (yjdF) from Escherichia coli (strain K12)

KEGG orthology group: K08984, putative membrane protein (inferred from 70% identity to esa:ESA_00954)

Predicted SEED Role

"Inner membrane protein yjdF"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (207 amino acids)

>IAI46_01420 DUF2238 domain-containing protein (Serratia liquefaciens MT49)
MSLLSARYLLPTAALLLIALLIYSGVYPYDRMTWLMEVMPVVIALVVLGLTRSRYPLTPL
LYQLIFLHALILIFGGMYSYARVPAGFYVQELLGLGRNPYDKLGHFFQGLVPALVAREIL
LRGDYVRGRKMLGFVVCCIALAISAVYELIEWWAALALGQGADEFLGTQGDPWDTQSDMF
CALLGAACGLLLFGRRQDRQLAGLSAK