Protein Info for IAI46_01090 in Serratia liquefaciens MT49

Annotation: Sec-independent protein translocase subunit TatC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 256 transmembrane" amino acids 20 to 39 (20 residues), see Phobius details amino acids 74 to 96 (23 residues), see Phobius details amino acids 116 to 137 (22 residues), see Phobius details amino acids 157 to 183 (27 residues), see Phobius details amino acids 195 to 212 (18 residues), see Phobius details amino acids 218 to 236 (19 residues), see Phobius details TIGR00945: twin arginine-targeting protein translocase TatC" amino acids 9 to 226 (218 residues), 258.8 bits, see alignment E=2.4e-81 PF00902: TatC" amino acids 11 to 221 (211 residues), 238 bits, see alignment E=4.7e-75

Best Hits

Swiss-Prot: 82% identical to TATC_ECOL6: Sec-independent protein translocase protein TatC (tatC) from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)

KEGG orthology group: K03118, sec-independent protein translocase protein TatC (inferred from 100% identity to spe:Spro_0253)

MetaCyc: 82% identical to twin arginine protein translocation system - TatC protein (Escherichia coli K-12 substr. MG1655)
TRANS-RXN0-181

Predicted SEED Role

"Twin-arginine translocation protein TatC" in subsystem Cluster-based Subsystem Grouping Hypotheticals - perhaps Proteosome Related or Twin-arginine translocation system

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (256 amino acids)

>IAI46_01090 Sec-independent protein translocase subunit TatC (Serratia liquefaciens MT49)
MAVEDTQPLISHLIELRKRLLNSIISILAIFLVLVFFANDIYQLVSAPLIKQLPAGASMI
ATDVASPFFTPIKLTMIVSVFVSAPVILYQVWSFIAPALYKHERRLMMPLLVSSSLLFYL
GMAFAYFIVFPLAFGFFAKTAPAGVMIATDINNYLDFVMALFMAFGVAFEVPVAIILLCW
SGVTSPEDLKKKRPYVLVGAFVVGMLLTPPDVFSQTLLAIPMYLLFEVGVFFARFYTGKR
RPQPEEEDEGDEPPTP