Protein Info for IAI46_01075 in Serratia liquefaciens MT49

Annotation: ubiquinone biosynthesis regulatory protein kinase UbiB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 543 transmembrane" amino acids 500 to 517 (18 residues), see Phobius details amino acids 523 to 539 (17 residues), see Phobius details TIGR01982: 2-polyprenylphenol 6-hydroxylase" amino acids 6 to 445 (440 residues), 594.5 bits, see alignment E=5e-183 PF03109: ABC1" amino acids 93 to 343 (251 residues), 254.4 bits, see alignment E=4.4e-80

Best Hits

Swiss-Prot: 99% identical to UBIB_SERP5: Probable protein kinase UbiB (ubiB) from Serratia proteamaculans (strain 568)

KEGG orthology group: K03688, ubiquinone biosynthesis protein (inferred from 99% identity to spe:Spro_0250)

Predicted SEED Role

"Ubiquinone biosynthesis monooxygenase UbiB" in subsystem Ubiquinone Biosynthesis

MetaCyc Pathways

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (543 amino acids)

>IAI46_01075 ubiquinone biosynthesis regulatory protein kinase UbiB (Serratia liquefaciens MT49)
MTPGELRRLYLIVRVFLSYGLDELIPKMRLTLPLRFGRRLLFWMPNRHADKPLGERLRLA
LQELGPVWIKFGQMMSTRRDLFPPQIADQLTLLQDRVAPFDGALARKHIELAMGGPLETW
FDDFDQQALASASIAQVHTARLKTTGQEVVLKVIRPDIGPIIKADVRLMYRLAAWVPKLM
PDGRRLRPREVVREYEKTLLDELNLLREAANAIQLRRNFDGSPMLYVPEVYSDYCRESVL
VMERIYGIPVSDIPTLEKQGTNMKLLAERGVQVFFTQVFRDSFFHADMHPGNIFVSYEHP
EDPCYIGIDCGIVGSLNKDDKRYLAENFIAFFNRDYRKVAELHVDSGWVPRDTNVEDFEF
AIRTVCEPIFEKPLSEISFGNVLLNLFNTARRFNMEVQPQLVLLQKTLLYVEGLGRQLYP
QLDLWTTAKPFLESWMRDQVGIPAVIRALKEKAPFWAEKLPELPELFYDSLQQHKLLQQS
VDKLTNQMQAQRVRQGQSRYLFGVGATLLVSGTILLLGDVEVFPAWLMAAGIVSWVIGWK
RTT