Protein Info for IAI46_00540 in Serratia liquefaciens MT49

Annotation: cellulose biosynthesis protein BcsC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1157 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details PF13432: TPR_16" amino acids 278 to 337 (60 residues), 24.1 bits, see alignment 2.3e-08 amino acids 359 to 421 (63 residues), 24 bits, see alignment 2.5e-08 amino acids 469 to 529 (61 residues), 16.1 bits, see alignment 7.3e-06 amino acids 610 to 670 (61 residues), 28.6 bits, see alignment 9.4e-10 PF14559: TPR_19" amino acids 290 to 337 (48 residues), 27.5 bits, see alignment (E = 1.8e-09) amino acids 364 to 429 (66 residues), 29.9 bits, see alignment 3.2e-10 amino acids 474 to 539 (66 residues), 33.9 bits, see alignment 1.8e-11 amino acids 616 to 669 (54 residues), 42.2 bits, see alignment 4.5e-14 PF13176: TPR_7" amino acids 309 to 336 (28 residues), 19.2 bits, see alignment (E = 5.6e-07) PF05420: BCSC_C" amino acids 805 to 1136 (332 residues), 405.4 bits, see alignment E=1.1e-124

Best Hits

Swiss-Prot: 55% identical to BCSC_ECOLI: Cellulose synthase operon protein C (bcsC) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 67% identity to eca:ECA4374)

Predicted SEED Role

"Cellulose synthase operon protein C"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1157 amino acids)

>IAI46_00540 cellulose biosynthesis protein BcsC (Serratia liquefaciens MT49)
MRNFRINWLGLVPLSLAMLPQAQGAETVAPEQWLLEQVRVGEAGNKDELVRQSLYRLELM
DPNNPEVISARMRLALRQGNLALAQQQLDKLKQIAPQSSSYRQAEMNMLLTQPETRQKLQ
QARLMATAGRLPEAKTQYDELFHGDPPTLELAVEYWRLVARLPGQEAAALKQLQTLDQQY
SGNVPLRMSLVRMLFSQDRDAQAYDLLQKVAADPAGRGDAADLWLEKVKAMPVSPQSVAA
LNRFLGVFETGDQAVSARQELARQQALLSDPAYQARVRGLAQVDKGGSRAAIPELKKALA
ASPNDADVLGALGQAYSRVGNRPQALSLFRQALQADKSGYGSSKWQSLIKSNSYWLAVDE
GDKALKAGNLALAQQKYQQARQIDNGDSSAVIGLGDVAVARKDDAAAERFYQQALRLDPG
SGSAVRGLVNIYQRQSPEKALAYLNSLPRGQQNKLRSTLEGLQLDMLKQQADQLVQQKQW
HQAAEKYRRAQQMDPDDVWLTYHYAQTLRQAGQPEQADALFSRLAQKQRANPQLAYAYAL
YLSGSDRDTQALSQLNTLPAAQWNDNMRELAQRLKMQATLEHADRLRTAGDEPGAVAYLR
RQPADTRIDLQLADWALARGEYDAALADYQRVRTREPNNPDARLGEIEAYVAQGKLSEAR
QRLQTAAPDPSESDNSGRRVANAWYAVGEPQKATEIFTRLKTTAQLAPPSQAKALIYRDA
ARLERDQQQPVLAQQDYKQAMVASGIAPSVPQDNDSYTYLTRNNPTDDWLKRGIRSDAAD
LYRQQDVNVTLDHDYWSSSGTGGISDYKAHDTMLQVDMPWYDGRAFFRSDTVQLDAGSFS
TDGSGKYYETFGTCNTQGCSGDERQKTTGTSVAVGWKNDRWAGDIGTTPMGFEVVDWVGG
LAYSNDWNHIGWTLAASRRPISSSLLAFGGTKDPNTGTTWGGVRATGVSLSASYDRGEAH
GVWADLSAHQLTGKNVEDNQRERFMAGYYYKLINEDNRRVTVGLNTMLWHYQKDLSGYSL
GQGGYYSPQQYMSLAIPVNYRQRTDNWSWELGGSVSLSHSKTNSQRRYPLQGLIPDSLPD
KFAVEDGSSSSGVGYTLRAIVERRLSSHWTLGAGIDIQQAKDYTPSHALIYLRYSLAGWQ
GDLDLPPQPLTPYADFK