Protein Info for IAI46_00535 in Serratia liquefaciens MT49

Annotation: cellulase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 370 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details PF01270: Glyco_hydro_8" amino acids 10 to 347 (338 residues), 320.2 bits, see alignment E=6.9e-100

Best Hits

Swiss-Prot: 61% identical to GUN_ECO57: Endoglucanase (bcsZ) from Escherichia coli O157:H7

KEGG orthology group: K01179, endoglucanase [EC: 3.2.1.4] (inferred from 94% identity to spe:Spro_0150)

MetaCyc: 61% identical to endo-1,4-D-glucanase (Escherichia coli K-12 substr. MG1655)
Cellulase. [EC: 3.2.1.4]

Predicted SEED Role

"Endoglucanase precursor (EC 3.2.1.4)" (EC 3.2.1.4)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.2.1.4

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (370 amino acids)

>IAI46_00535 cellulase (Serratia liquefaciens MT49)
MPARLKRLTIGMLLLCAFSAAAACEWPAWQQYKQFYISEQGRVIDPSSPNRITTSEGQSY
GLFFALVANDRPAFDQLLTWTENNLAAGDLSAHLPAWLWGENEQKQWTVLDSNSASDADL
WIAYNLLEAGRLWKSRRYQTLGTLLLQRIAREEVADIPGLGLMLLPGKVGFVAEDRWRLN
PSYLPPQLLARFAVLNGPWRKMQQTNQRLWLETAPHGFSPDWVVWQVGKGWQPDTVKPNI
GSYDAIRVYLWAGMLADDDEHKAALLKQLQPMAQLTAQQGVPPEKTDTASGKTHGDGPVG
FSASMLPMLAHEPEALQVQRQRIKQNPPGDRAYFSASLALFGQGWDQQRYRFNRQGELQP
SWGGQCVTSE