Protein Info for IAI46_00295 in Serratia liquefaciens MT49

Annotation: sugar ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 394 transmembrane" amino acids 26 to 47 (22 residues), see Phobius details amino acids 61 to 82 (22 residues), see Phobius details amino acids 88 to 108 (21 residues), see Phobius details amino acids 112 to 133 (22 residues), see Phobius details amino acids 139 to 158 (20 residues), see Phobius details amino acids 177 to 199 (23 residues), see Phobius details amino acids 219 to 236 (18 residues), see Phobius details amino acids 242 to 261 (20 residues), see Phobius details amino acids 291 to 312 (22 residues), see Phobius details amino acids 327 to 358 (32 residues), see Phobius details amino acids 369 to 387 (19 residues), see Phobius details PF02653: BPD_transp_2" amino acids 57 to 384 (328 residues), 141.3 bits, see alignment E=1.7e-45

Best Hits

Swiss-Prot: 86% identical to XYLH_ECO57: Xylose transport system permease protein XylH (xylH) from Escherichia coli O157:H7

KEGG orthology group: K10544, D-xylose transport system permease protein (inferred from 96% identity to spe:Spro_0101)

MetaCyc: 86% identical to xylose ABC transporter membrane subunit (Escherichia coli K-12 substr. MG1655)
ABC-33-RXN [EC: 7.5.2.10, 7.5.2.13]

Predicted SEED Role

"Xylose ABC transporter, permease protein XylH" in subsystem Xylose utilization

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.5.2.10 or 7.5.2.13

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (394 amino acids)

>IAI46_00295 sugar ABC transporter permease (Serratia liquefaciens MT49)
MSKNTQSEALVAARVEKKTTVKLKSINLQVFVMLAAIVVIMLFFTFTTEGAYLSARNISN
LLRQTAITGILAVGMVFVIVSAEIDLSVGSMMGLLGGAAAIFDVWFGWPLPLTIVVTLVA
SLLLGAWNGWWVAYRKVPSFIVTLAGMLAFRGILIGITNGTTVAPTSGAMSQIGQSYLPG
GLGFGIGAVGLMLFVAWQWRRRSRRVQLGLPVATPTGDVTRQSILALLVLGAIYLLNDYR
GVPTPVLILTALMLAGIFMATRTAFGRRIYAIGGNIDAARLSGVNVERTKLAVFAINGLM
VAIAGLILSSRLGAGSPSAGNIAELDAIAACVIGGTSLAGGIGSVAGAVMGAFIMASLDN
GMSMLDVPTFWQYIVKGAILLLAVWMDSATKRRA