Protein Info for IAI46_00030 in Serratia liquefaciens MT49

Annotation: ornithine cyclodeaminase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF02423: OCD_Mu_crystall
  • amino acids 17 to 309 (293 residues), 171.4 bits, E=2.5e-54
• PF01488: Shikimate_DH
  • amino acids 131 to 214 (84 residues), 24.3 bits, E=2.8e-09

Best Hits

KEGG orthology group: K01750, ornithine cyclodeaminase [EC: 4.3.1.12] (inferred from 82% identity to srs:SerAS12_0006)

Predicted SEED Role

"Ornithine cyclodeaminase (EC 4.3.1.12)" in subsystem Arginine and Ornithine Degradation (EC 4.3.1.12)

MetaCyc Pathways

• L-arginine degradation VII (arginase 3 pathway) (2/2 steps found)
• L-ornithine degradation I (L-proline biosynthesis) (1/1 steps found)
• L-proline biosynthesis II (from arginine) (1/2 steps found)

KEGG Metabolic Maps

• Arginine and proline metabolism

Isozymes

Compare fitness of predicted isozymes for: 4.3.1.12

Use Curated BLAST to search for 4.3.1.12

Protein Sequence (313 amino acids)

>IAI46_00030 ornithine cyclodeaminase family protein (Serratia liquefaciens MT49)
MKILNKRQILEAFDADATTLLLKEGFIAYSKRQVQQPPVQHFLFEQAAGDCCIKSAWLEG
DEQFVLKVSSGFYRNPAQGLASNQGLMMAFSAQTGEPQALLLDEGWLTALRTALAGRIVA
ELCAPTEIPAIGIVGCGMQALLQLQQLKPLTACREVWVWGRNESALQAYRHSAEAEGFRV
HTTQDAAELAAHCRLIITTTPSREPILRATDIRPGTHITAVGADSHGKQELESGLVARAD
VLLADSVSQCTEYGEIAMAYRQGLLASIPLVELGTVLAQGKKVRSDPEQITLADLTGLAI
QDVQIVKGILARL