Protein Info for HUW76_10140 in Fusobacterium nucleatum SB010

Annotation: cell envelope integrity protein CreD

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 476 transmembrane" amino acids 24 to 45 (22 residues), see Phobius details amino acids 340 to 358 (19 residues), see Phobius details amino acids 365 to 385 (21 residues), see Phobius details amino acids 392 to 411 (20 residues), see Phobius details amino acids 419 to 438 (20 residues), see Phobius details amino acids 443 to 462 (20 residues), see Phobius details PF06123: CreD" amino acids 20 to 467 (448 residues), 433.2 bits, see alignment E=5.6e-134

Best Hits

KEGG orthology group: K06143, inner membrane protein (inferred from 86% identity to fnu:FN1985)

Predicted SEED Role

"Inner membrane protein CreD-like protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (476 amino acids)

>HUW76_10140 cell envelope integrity protein CreD (Fusobacterium nucleatum SB010)
MDNNLQPQMPPYARRRVSPVTKKIIFLFVLTILLWIPLILIGNLINDRGKLYKQTITNIG
NEWGKSQKIIAPVITISYTDTSINNKDSVSNASNTKAVAVVPVERKFAILPEELNATIEM
KDEVRQRGIYNATVYNANVKLKGYFSAKDFPEDKKVLGCVSIGLTDTKALIKINKFKIGD
MDLEAMSGTMAAPLITNGISGQLGPEHNNMMDKEKIPFEIDIDFRGSRDISILPLGKKNH
FEIKSNWKSPSFSGVLPTERTIDNNGFSAVWEVSNLIRNYPQIIDINNDQFSDFYQDGVV
YNEYDDETTYSDNNDENTIVKVALFDSVTSYTQIYRACNYGILFIGMSLVVVFIFEIVSK
KAAHYVQYGVVGFSLVIFYLLLLSLSEHIGFEWSYLVSSLAIVIPNSLYITSMTSSKKFG
IGMFIFLSGIYAILFSILRMEQYALLTGSLLILAVLYAVMYLTKKADVFQSLEGKE