Protein Info for HUW76_09290 in Fusobacterium nucleatum SB010

Annotation: riboflavin synthase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR00187: riboflavin synthase, alpha subunit
  • amino acids 1 to 197 (197 residues), 229.5 bits, E=1.2e-72
• PF00677: Lum_binding
  • amino acids 3 to 85 (83 residues), 75.3 bits, E=1.6e-25
  • amino acids 99 to 183 (85 residues), 82.4 bits, E=9.8e-28

Best Hits

Swiss-Prot: 51% identical to RISA_ACTPL: Riboflavin synthase (ribE) from Actinobacillus pleuropneumoniae

KEGG orthology group: K00793, riboflavin synthase [EC: 2.5.1.9] (inferred from 95% identity to fnu:FN1507)

MetaCyc: 44% identical to riboflavin synthase monomer (Bacillus subtilis)
Riboflavin synthase. [EC: 2.5.1.9]

Predicted SEED Role

"Riboflavin synthase eubacterial/eukaryotic (EC 2.5.1.9)" (EC 2.5.1.9)

MetaCyc Pathways

• flavin biosynthesis I (bacteria and plants) (8/9 steps found)
• flavin biosynthesis III (fungi) (7/9 steps found)
• flavin biosynthesis II (archaea) (5/10 steps found)

KEGG Metabolic Maps

• Riboflavin metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.5.1.9

Protein Sequence (218 amino acids)

>HUW76_09290 riboflavin synthase (Fusobacterium nucleatum SB010)
MFTGLVEEKGNVISLNNGDKSIKLKIKANKVLENVKLGDSIATNGVCLTVTEFSKDYFIA
DCMFETISRSNLKRLKAGDEVNLEKSITLSTPLGGHLVTGDVDCEGEIVSIIQEGIAKIY
EIKISRKYMRYIVEKGRVTIDGASLTVISLTDDTFSVSLIPHTQEKIVLGSKKVGDIVNI
ETDLVGKYIERFVYFDKLEKKENKKSKISREFLLENGF