Protein Info for HUW76_09000 in Fusobacterium nucleatum SB010

Annotation: restriction endonuclease subunit S

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 605 PF01420: Methylase_S" amino acids 13 to 192 (180 residues), 107.6 bits, see alignment E=8.1e-35 amino acids 212 to 391 (180 residues), 69.7 bits, see alignment E=3.7e-23 amino acids 438 to 587 (150 residues), 110.6 bits, see alignment E=9.7e-36

Best Hits

Predicted SEED Role

"Type I restriction-modification system, specificity subunit S (EC 3.1.21.3)" in subsystem Restriction-Modification System (EC 3.1.21.3)

Isozymes

Compare fitness of predicted isozymes for: 3.1.21.3

Use Curated BLAST to search for 3.1.21.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (605 amino acids)

>HUW76_09000 restriction endonuclease subunit S (Fusobacterium nucleatum SB010)
MSKLDELIKELCPNGVEYKKLGEVCNFQNGFAFKSALFKENGEAILRITNISNGIINEED
LKYFLLDDYKENLDNYIVSKNDIVIAMSGATTGKIGINNTSKKFYLNQRVGKFIPNIVKL
NSRFLYHFLLSKSLEILKISSGSGAQPNLSTENIKNLVIPVLPLEVQEEIAKILDNYTKS
VEELKEKLNEELIARKNQYSWYRDYLLKFENKIKTVKLGDISSIVRGASPRPISNYITFE
EDGVNWIKIGDVNPESKYVEKTKEKITLEGAKKSRIVKKGDLILSNSMSFGRPYIVNQKG
CIHDGWILISDYQTSYSTDFLYYLLTSNKVQKYMRDNVISGTVQNLNTDIVKNIEIPLLS
LEVQKRIVEVLDNFEKICNDLNIGLPAEIEARQKQYEFYRNFLLTFKIENCTLPKTRQDK
TRQDIIKLFMYIFGYIELELGEILKIKNGSDYKKFNIGNIPVYGSGGIINYIDTYIYDKE
SVLIPRKGSIGNLFYVDKPFWTVDTIFYTVIDKDIVIPKYVYYYLSKVNLEKLNTAGGVP
SLTQTVLNKILIPLPPLEEQQRIVDILDRFDKLCNDISEGLPAEIEARQKQYEYYREKLL
TFKKL