Protein Info for HUW76_08115 in Fusobacterium nucleatum SB010

Annotation: ABC transporter substrate-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 382 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details PF13458: Peripla_BP_6" amino acids 33 to 370 (338 residues), 236.9 bits, see alignment E=8e-74 PF13433: Peripla_BP_5" amino acids 34 to 380 (347 residues), 93.8 bits, see alignment E=1.8e-30 PF01094: ANF_receptor" amino acids 56 to 368 (313 residues), 130.4 bits, see alignment E=1.2e-41

Best Hits

KEGG orthology group: K01999, branched-chain amino acid transport system substrate-binding protein (inferred from 92% identity to fnu:FN1432)

Predicted SEED Role

"Branched-chain amino acid ABC transporter, amino acid-binding protein (TC 3.A.1.4.1)" in subsystem ABC transporter branched-chain amino acid (TC 3.A.1.4.1) (TC 3.A.1.4.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (382 amino acids)

>HUW76_08115 ABC transporter substrate-binding protein (Fusobacterium nucleatum SB010)
MKKKFLTALLGASLLLVACGGEKTEEKPAEAETIKIGAMGPLTGPVAIYGISATNGLKLA
IDEINANGGILGKQVELNLLDEKGDSTEAVNAYNKLVDWGMVALVGDITSKPTVAVSEVA
AQDGIPMITPTGTQLNITEAGSNVFRVCFTDPYQGEVLAKFTKDKLGAKTVAVMSNNSSD
YSDGVANAFIKEAENQGIQVVAKEGYSDGDKDFRAQLTKIAQQNPDVLFIPDYYEQDGLI
AIQAREVGLKSVIVGSDGWDGVVKTVDPSSYAAIENVYFANHYSTKDSNEKIQNFIKNYK
EKYNDEPSAFSALSYDTAYLLKAAIEKAGTTDKEAVTKAIKEIQFEGITGKLTFDEKNNP
VKSITIIKIVNGDYTFDSVVSK