Protein Info for HUW76_07080 in Fusobacterium nucleatum SB010

Annotation: ABC transporter ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 220 PF00005: ABC_tran" amino acids 22 to 170 (149 residues), 126.2 bits, see alignment E=1.5e-40

Best Hits

Swiss-Prot: 57% identical to YVRO_BACSU: Uncharacterized ABC transporter ATP-binding protein YvrO (yvrO) from Bacillus subtilis (strain 168)

KEGG orthology group: K09810, lipoprotein-releasing system ATP-binding protein [EC: 3.6.3.-] (inferred from 98% identity to fnu:FN0827)

MetaCyc: 47% identical to lipoprotein release complex - ATP binding subunit (Escherichia coli K-12 substr. MG1655)
RXN-22427

Predicted SEED Role

"ABC transporter ATP-binding protein"

MetaCyc Pathways

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.-

Use Curated BLAST to search for 3.6.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (220 amino acids)

>HUW76_07080 ABC transporter ATP-binding protein (Fusobacterium nucleatum SB010)
MIITVDNINKTYKNGSLELQVLKNISFKVDKGEFLAIMGSSGSGKSTMMNILGCLDNQYE
GRYILDGIDISKSTENELSEIRNKKIGFIFQSFNLLPRLTALENVELPLVYSSIPKEERH
KRANELLEMVGLKERIHHRPNELSGGQRQRVAIARALANNPSIILADEPTGNLDSKSEEE
IIEILQKLNKMGKTIVIVTHEPSIGEIAERKIVFKDGEII