Protein Info for HUW76_07040 in Fusobacterium nucleatum SB010

Annotation: MATE family efflux transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 448 transmembrane" amino acids 20 to 43 (24 residues), see Phobius details amino acids 58 to 79 (22 residues), see Phobius details amino acids 94 to 115 (22 residues), see Phobius details amino acids 135 to 157 (23 residues), see Phobius details amino acids 169 to 188 (20 residues), see Phobius details amino acids 194 to 216 (23 residues), see Phobius details amino acids 252 to 273 (22 residues), see Phobius details amino acids 285 to 305 (21 residues), see Phobius details amino acids 318 to 339 (22 residues), see Phobius details amino acids 358 to 377 (20 residues), see Phobius details amino acids 389 to 409 (21 residues), see Phobius details amino acids 415 to 438 (24 residues), see Phobius details PF03023: MurJ" amino acids 10 to 217 (208 residues), 37.3 bits, see alignment E=2e-13 TIGR00797: MATE efflux family protein" amino acids 23 to 420 (398 residues), 268.3 bits, see alignment E=5.6e-84 PF01554: MatE" amino acids 23 to 184 (162 residues), 81.7 bits, see alignment E=7.6e-27 amino acids 246 to 407 (162 residues), 101.3 bits, see alignment E=7.2e-33 PF14667: Polysacc_synt_C" amino acids 142 to 215 (74 residues), 35.1 bits, see alignment E=2.1e-12

Best Hits

KEGG orthology group: None (inferred from 69% identity to fnu:FN1151)

Predicted SEED Role

"FIG00671799: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (448 amino acids)

>HUW76_07040 MATE family efflux transporter (Fusobacterium nucleatum SB010)
MNIEKSIIANKKLIKNIFQITIPAVFDLLAQTLIMAFDMMMVASLGPTAISSVGVGTAAM
YALIPALIAVATGTTALLSRAFGANNKIEGKKAFAQSFFIAIPLGIFLTVMFLIFSKEII
NLVGNAKDMNLKDAILYQNMTVIGFPFLAISISTFYAFRAMGENKIPMIGNTLALILKIL
LNYLLIHIFKWGVFGAALSTTLTRLSSAIFSIYLVFWSKKNWISLQIKDLKFDYFTAKRI
LKVGIPAAMEQLGLRIGMLIFEMMVISLGNLAYAAHKIALTAESISYNLGFAFAFAASAL
VGQELGKGSSKKALKDGYICTMIAMIVMSTFGLLFFIMPHFLVSLFTDDKKVIELSTTAL
KIVSICQPFSGASLVLAGSLRGAGDTKSVLFITFLGIFLIRIPTTYLFLDILNFGLAGAW
IVMTIDLFIRSSLLYYVFKRGKWKYLQV