Protein Info for HUW76_06700 in Fusobacterium nucleatum SB010

Annotation: RNase adapter RapZ

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 290 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details PF03668: RapZ-like_N" amino acids 5 to 152 (148 residues), 130.2 bits, see alignment E=6.3e-42 PF22740: PapZ_C" amino acids 163 to 285 (123 residues), 156.4 bits, see alignment E=3.6e-50

Best Hits

Swiss-Prot: 94% identical to Y1089_FUSNN: Nucleotide-binding protein FN1089 (FN1089) from Fusobacterium nucleatum subsp. nucleatum (strain ATCC 25586 / CIP 101130 / JCM 8532 / LMG 13131)

KEGG orthology group: K06958, UPF0042 nucleotide-binding protein (inferred from 94% identity to fnu:FN1089)

Predicted SEED Role

"Hypothetical ATP-binding protein UPF0042, contains P-loop"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (290 amino acids)

>HUW76_06700 RNase adapter RapZ (Fusobacterium nucleatum SB010)
MKTKHIIIVTGLSGAGKTTALNILEDMNYYTIDNLPLGLEKSLLDTEIEKLAVGIDIRTF
KNTKDFFKFINYIKETGVKMDIIFLEAHEAIILGRYTLSRRAHPLKEVTLLRSILKEKKI
LFPIKEIADLIIDTTEIKNVELEKRIKKFILAKDEENIDVNINIHIQSFGYKYGIPTDSD
LMFDVRFIPNPYYIEKLKELNGFDEEVKEYVLSQKESEEFYSKLLPLLEFLIPQYIKEGK
KHLTISIGCSGGQHRSVTFVNKLAEDLKNSKVLKHINIYVSHREKELGHW