Protein Info for HUW76_05415 in Fusobacterium nucleatum SB010

Annotation: sulfite reductase subunit C

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 324 TIGR02912: sulfite reductase, subunit C" amino acids 4 to 317 (314 residues), 514.3 bits, see alignment E=4.8e-159 PF03460: NIR_SIR_ferr" amino acids 19 to 80 (62 residues), 63.7 bits, see alignment E=5.3e-21 PF01077: NIR_SIR" amino acids 100 to 303 (204 residues), 99.4 bits, see alignment E=7.5e-32 PF13237: Fer4_10" amino acids 169 to 217 (49 residues), 25.9 bits, see alignment 4.2e-09 amino acids 198 to 225 (28 residues), 25.4 bits, see alignment (E = 5.9e-09) PF14697: Fer4_21" amino acids 171 to 218 (48 residues), 36.8 bits, see alignment 1.8e-12 PF13187: Fer4_9" amino acids 173 to 219 (47 residues), 28.6 bits, see alignment 5.7e-10 PF12837: Fer4_6" amino acids 198 to 221 (24 residues), 30.4 bits, see alignment (E = 1.3e-10) PF00037: Fer4" amino acids 200 to 220 (21 residues), 26.2 bits, see alignment (E = 2.5e-09)

Best Hits

Swiss-Prot: 40% identical to ASRC_SALTY: Anaerobic sulfite reductase subunit C (asrC) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: K00385, anaerobic sulfite reductase subunit C [EC: 1.8.1.-] (inferred from 78% identity to cdl:CDR20291_2130)

MetaCyc: 40% identical to AsrC monomer (S. enterica) (Salmonella enterica enterica serovar Typhimurium)

Predicted SEED Role

"Anaerobic sulfite reductase subunit C (EC 1.8.1.-)" in subsystem Anaerobic respiratory reductases (EC 1.8.1.-)

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.8.1.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (324 amino acids)

>HUW76_05415 sulfite reductase subunit C (Fusobacterium nucleatum SB010)
MIRDLNTKKVMKNAFRITKTKYKTALRVRVPGGLIDPECLMLVSEISSKYGDGQIHITTR
QGFEILGIDMEDMPAVNEMAQPLIDKLNINQDEKGKGYSAAGTRNVSACIGNKVCPKAQY
NTTNFAKRIEKAIFPNDLHFKVALTGCPNDCIKARMHDFGIIGTCLPEYEMDRCVACGAC
VKKCKKLSVEALKMENNKIVRDANKCIGCGECVINCPMSAWTRSPKKYYKLMIMGRTGKK
NPRLAEDWLRWVDEDSIVKIIENTYHYVKEYISKDAPNGKEHIGYIVDRTGFQEFRKWAL
KDVNLPKETVEKQNIYWSGPKYDY