Protein Info for HUW76_03525 in Fusobacterium nucleatum SB010

Annotation: ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 289 signal peptide" amino acids 1 to 43 (43 residues), see Phobius details transmembrane" amino acids 93 to 115 (23 residues), see Phobius details amino acids 126 to 146 (21 residues), see Phobius details amino acids 151 to 169 (19 residues), see Phobius details amino acids 205 to 233 (29 residues), see Phobius details amino acids 253 to 276 (24 residues), see Phobius details PF12911: OppC_N" amino acids 10 to 64 (55 residues), 60.8 bits, see alignment E=9e-21 PF00528: BPD_transp_1" amino acids 105 to 288 (184 residues), 126.8 bits, see alignment E=8.6e-41

Best Hits

Swiss-Prot: 43% identical to DDPC_ECOLI: Probable D,D-dipeptide transport system permease protein DdpC (ddpC) from Escherichia coli (strain K12)

KEGG orthology group: K02034, peptide/nickel transport system permease protein (inferred from 97% identity to fnu:FN0398)

MetaCyc: 38% identical to nickel ABC transporter membrane subunit NikC (Escherichia coli K-12 substr. MG1655)
7.2.2.i [EC: 7.2.2.i]; 7.2.2.- [EC: 7.2.2.i]

Predicted SEED Role

"Dipeptide transport system permease protein DppC (TC 3.A.1.5.2)" in subsystem ABC transporter dipeptide (TC 3.A.1.5.2) (TC 3.A.1.5.2)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.2.2.i

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (289 amino acids)

>HUW76_03525 ABC transporter permease (Fusobacterium nucleatum SB010)
MEKTKNKKQSQWAEVFRMLKKNRMAMLGLIILVILVLLALFADVIANYDAVVIKQNLAER
LMPPNGEHWLGTDEFGRDIFARLIHGARVSLKVGILAISISVIVGGILGAISGYFGGVID
NIIMRIVDIFLAVPSILLAIAIVSALGPSMLNLMISISVSYVPNFARIVRASVLSIRDQE
FIEAAKAIGASNSRIIMKHIIPNSLAPVIVQGTLGVAGAILSTAGLSFIGLGIQPPAPEW
GSMLSGGRQYLRYAWWVTTFPGVAIMITILSLNLLGDGLRDALDPRLKQ