Protein Info for HUW76_03135 in Fusobacterium nucleatum SB010
Annotation: Gx transporter family protein
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K00805, heptaprenyl diphosphate synthase [EC: 2.5.1.30] (inferred from 95% identity to fnu:FN0367)Predicted SEED Role
"Heptaprenyl diphosphate synthase component I (EC 2.5.1.30)" in subsystem Polyprenyl Diphosphate Biosynthesis or Sex pheromones in Enterococcus faecalis and other Firmicutes (EC 2.5.1.30)
MetaCyc Pathways
- superpathway of geranylgeranyl diphosphate biosynthesis II (via MEP) (9/12 steps found)
- geranylgeranyl diphosphate biosynthesis (1/1 steps found)
- heptaprenyl diphosphate biosynthesis (1/1 steps found)
- ophiobolin F biosynthesis (2/3 steps found)
- taxadiene biosynthesis (engineered) (9/13 steps found)
- methyl phomopsenoate biosynthesis (2/4 steps found)
- plaunotol biosynthesis (1/3 steps found)
- stellatic acid biosynthesis (4/8 steps found)
- superpathway of geranylgeranyldiphosphate biosynthesis I (via mevalonate) (4/10 steps found)
- paspaline biosynthesis (1/6 steps found)
- brassicicene C biosynthesis (1/7 steps found)
- superpathway of menaquinol-7 biosynthesis (3/10 steps found)
- fusicoccin A biosynthesis (1/8 steps found)
- C25,25 CDP-archaeol biosynthesis (1/10 steps found)
- superpathway of phylloquinol biosynthesis (4/15 steps found)
- Methanobacterium thermoautotrophicum biosynthetic metabolism (16/56 steps found)
KEGG Metabolic Maps
Isozymes
Compare fitness of predicted isozymes for: 2.5.1.30
Use Curated BLAST to search for 2.5.1.30
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (172 amino acids)
>HUW76_03135 Gx transporter family protein (Fusobacterium nucleatum SB010) MIKREYREEIYLIALVLLGLYLSLIENIIPKPFPWMKIGLSNISVLIALEKFNSKMALQT ILLRVFIQALMLGTLFTPNFIISFSAGLVSTLFMIFLYKFRKYLSLLSISCISAFTHNLL QLIVVYFLLFRNISLNSKSIIIFIVIFLGLGVIMGLITGVIATKINLKRKKI