Protein Info for HUW76_02680 in Fusobacterium nucleatum SB010

Annotation: ABC transporter substrate-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 351 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details PF13531: SBP_bac_11" amino acids 50 to 296 (247 residues), 53.9 bits, see alignment E=4.5e-18 PF01547: SBP_bac_1" amino acids 54 to 293 (240 residues), 58.7 bits, see alignment E=2.1e-19 PF13416: SBP_bac_8" amino acids 58 to 303 (246 residues), 67.7 bits, see alignment E=3.1e-22 PF13343: SBP_bac_6" amino acids 100 to 311 (212 residues), 76.5 bits, see alignment E=4.5e-25

Best Hits

KEGG orthology group: K02012, iron(III) transport system substrate-binding protein (inferred from 97% identity to fnu:FN0308)

Predicted SEED Role

"Iron(III)-binding protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (351 amino acids)

>HUW76_02680 ABC transporter substrate-binding protein (Fusobacterium nucleatum SB010)
MKKKFFWLVLSLMTLFLVACGGGEKKEEATDSNANTEITGKIVIYTSMYEDIIDNVSEKL
KKEFPNLEVEFFQGGTGTLQSKIIAELQANKLGCDMLMVAEPSYSLELKEKGILHPYISK
NAENLALDYDKEGYWYPVRLLNMVLAYNPDKYKKEDLALTFEDFAKREDLKGKISIPDPL
KSGTALAAVSALSDKYGEEYFQNLAKLKVVVESGSVAVTKLETGEAAEIMILEESILKKR
EEENSTLEVIYPEDGIISIPSTIMTVKEDMSANKNIKAAEALTDWFLSPAGQEAIVEGWM
HSVLKNPEKAPYDAKATDEILKSSMPINWEKTYKDREELRKMFEKFITKAN