Protein Info for HUW76_01575 in Fusobacterium nucleatum SB010

Annotation: TIGR00282 family metallophosphoesterase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 263 PF00149: Metallophos" amino acids 1 to 177 (177 residues), 27.4 bits, see alignment E=4.5e-10 TIGR00282: metallophosphoesterase, MG_246/BB_0505 family" amino acids 1 to 259 (259 residues), 296.8 bits, see alignment E=7.1e-93 PF13277: YmdB" amino acids 4 to 253 (250 residues), 354.4 bits, see alignment E=3.1e-110

Best Hits

Swiss-Prot: 50% identical to YMDB_BACSU: 2',3'-cyclic-nucleotide 2'-phosphodiesterase (ymdB) from Bacillus subtilis (strain 168)

KEGG orthology group: K09769, hypothetical protein (inferred from 99% identity to fnu:FN1609)

Predicted SEED Role

"FIG006542: Phosphoesterase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (263 amino acids)

>HUW76_01575 TIGR00282 family metallophosphoesterase (Fusobacterium nucleatum SB010)
MKVLVVGDIVGRPGRNTLQVFLEKYKDNYDFIIVNGENSAGGFGITIKITDEFLSWGVDV
ISGGNHSWDKKEIYEYMNNSDRILRPANYPEGVSGKGYTILEDKKGNKIALISLQGRVFM
SAVDCPFRTAKKLIDEISKITKNIIVDFHAEATSEKIALGKYLDGDISLFYGTHTHVQTA
DERILNNGTGYISDIGMTGSQNGVIGTNLETIINKFLTSLPQKFEVAEGDEQLCGIEVEI
DEKTGKCQKIERIKWSENEGFRS