Protein Info for HUW76_01375 in Fusobacterium nucleatum SB010

Annotation: glycosyltransferase family 4 protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 413 transmembrane" amino acids 83 to 100 (18 residues), see Phobius details PF13579: Glyco_trans_4_4" amino acids 61 to 204 (144 residues), 40.5 bits, see alignment E=7.5e-14 PF13439: Glyco_transf_4" amino acids 88 to 208 (121 residues), 55.2 bits, see alignment E=1.9e-18 PF00534: Glycos_transf_1" amino acids 218 to 385 (168 residues), 52.9 bits, see alignment E=6.5e-18 PF13692: Glyco_trans_1_4" amino acids 229 to 368 (140 residues), 55 bits, see alignment E=2.3e-18

Best Hits

KEGG orthology group: None (inferred from 36% identity to csc:Csac_1092)

Predicted SEED Role

"Probable glycosyl transferase (EC 2.4.-.-)" (EC 2.4.-.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.4.-.-

Use Curated BLAST to search for 2.4.-.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (413 amino acids)

>HUW76_01375 glycosyltransferase family 4 protein (Fusobacterium nucleatum SB010)
MNKKSIWLISQYSYPPGKSSWRRHFDLFRHFNKNKYNIDIVSGSFLHNSENQHILKEDEK
ERIIEAEGIKYHILRVMSYSKRLDRIIAMIQFFFKVIFFSKKLLKDSKPDIIIASSPHPF
NGLAGMYLAKKYKCPFIIEIRDLWPETWVAMGATTRKSILYKFFAYIEKKLYKNADKIIT
LTANKDYYTSIGIDGKKVEIISNGVDLESYDSNLKEYKSPLTFSKDNFNILYTGSHSQGD
ALDILIETAELLSKEKIVFHLVGEGVIKEELKKRVKENNINNVKFYDIVKKYEIPSLLKE
SDAVIMLLRDIPLYKYGMSPNKMYEYLASTKPIIFSGSVANDMVKEANAGVSVEAENPKK
LKEGILSLQKMTIDEREVLGKKGRKYVEENYDTKVLSKKIEKIILNLLEDKNV