Protein Info for HUW76_01295 in Fusobacterium nucleatum SB010

Annotation: autotransporter phospholipase A1 FplA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 760 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details PF01734: Patatin" amino acids 65 to 256 (192 residues), 126.5 bits, see alignment E=1.5e-40 PF01103: Omp85" amino acids 463 to 746 (284 residues), 36.7 bits, see alignment E=3.8e-13

Best Hits

KEGG orthology group: K01362, [EC: 3.4.21.-] (inferred from 82% identity to fnu:FN1704)

Predicted SEED Role

"FIG00669905: hypothetical protein"

Isozymes

Compare fitness of predicted isozymes for: 3.4.21.-

Use Curated BLAST to search for 3.4.21.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (760 amino acids)

>HUW76_01295 autotransporter phospholipase A1 FplA (Fusobacterium nucleatum SB010)
MKKIFFLIYIFLNFGFAYSENIELKSREDVEIENLENQIKVLEDKIQTIKKLKNDKNKND
LKVGLVLSGGGIKGYAHLGVLRVLERENIKIDYITGTSIGALVGTLYSIGYSVDDIEKVL
DKINVKNFLETGSDTTNLPLDKKESLKKYSLHVNFDNELNFSLPKGLKGNRETYLVVKDL
LKNYANIKNFDDFPIPLRIIATNLNTGETKAFSKGDISKILIASMAIPTIFEPVEIDGNI
YVDGLVSRNLPVEEAYDMGADLVVASDIGAPIVKKDNYNILSVLNQISTIQSSNITKVSR
EKASILISPDVKDISAIDSSKKNDLINLGKVAAEQQIAKIKELPKSSSNRKIVKNIEDKK
EKFVINKIEYNKKFDNNTVEILDNTFKNLLNKPISEKDIENTITEVYNLKYMDKVYYTIN
DNVLYLDGEKAHSNRIGVGANYQTGYGTTFNIGTDLFFNGKFGNNINLNFKFGDYLGLDL
GTLTYHSIKNRFGILTNIGYNESPFFLYDNRKKIAKFMNREAYLNVGIFTQPSNNSMISY
GVISKFSNLKQDTGGNLSRNLEYSENQTKTYLRFKYDNLDSISNPMKGIKADLIYNFAGS
FGKSKSNLYGPAYSIKGYVPINPKSSFIYGLNLASLRGDRIRADQRIRLGGIYTNINDNE
FEFYGFNYQEKQVKDLISLTLGFKHKIVYSLYFNTKFNIATFTENNPLENNNSRLWKNYS
KGVGVSISYDSPIGPIEFSISSDLKHRKPIGSISIGYKLD