Protein Info for HUW76_01155 in Fusobacterium nucleatum SB010

Annotation: ArsB/NhaD family transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 425 signal peptide" amino acids 1 to 17 (17 residues), see Phobius details transmembrane" amino acids 26 to 42 (17 residues), see Phobius details amino acids 54 to 80 (27 residues), see Phobius details amino acids 94 to 124 (31 residues), see Phobius details amino acids 134 to 153 (20 residues), see Phobius details amino acids 173 to 194 (22 residues), see Phobius details amino acids 224 to 244 (21 residues), see Phobius details amino acids 247 to 259 (13 residues), see Phobius details amino acids 278 to 301 (24 residues), see Phobius details amino acids 313 to 338 (26 residues), see Phobius details amino acids 359 to 385 (27 residues), see Phobius details amino acids 401 to 422 (22 residues), see Phobius details PF02040: ArsB" amino acids 7 to 422 (416 residues), 79.5 bits, see alignment E=6.9e-26 PF00939: Na_sulph_symp" amino acids 7 to 191 (185 residues), 35.9 bits, see alignment E=9.4e-13 amino acids 275 to 414 (140 residues), 30.1 bits, see alignment E=5.6e-11 PF03600: CitMHS" amino acids 15 to 367 (353 residues), 249.6 bits, see alignment E=9.8e-78 PF06450: NhaB" amino acids 138 to 254 (117 residues), 27.4 bits, see alignment E=3.2e-10

Best Hits

KEGG orthology group: None (inferred from 95% identity to fnu:FN1924)

Predicted SEED Role

"Na+/H+ antiporter NhaD type" in subsystem Na(+) H(+) antiporter

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (425 amino acids)

>HUW76_01155 ArsB/NhaD family transporter (Fusobacterium nucleatum SB010)
MLLILGILIFIIVFYCIITEKVPSAYATMLGALAMAFLGIVNEEEILETIHSRLEILLLL
IGMMIIVSLISETGVFQWFAIKVVKIVRGDPLKLLILLSLVTATCSAFLDNVTTILLMAP
VSILLAKQLELDPFPFVMTEVLSSDIGGMATLIGDPTQLIIGSEGKLNFNEFLFNTAPMT
VIALIILLTIVYFTNIRKMKVPNRLRAQIMELESERILKDKKLLKQSMIILSAVIIGFVL
NNFVNKGLSVISLSGGIFLAFLTEREPKKIFGGVEWDTLFFFIGLFIMIKGIENLGVIKF
IGDKIIEISTGNFKVATISIMWLSSMFTSIFGNVANAATFSKIIKTVIPGFQNVANTKVF
WWALSFGSCLGGSITMIGSATNVVAVSASAKAGCKIDFIKFFKFGAKIAILNLIAASVYM
YLRYL