Protein Info for HUW76_00105 in Fusobacterium nucleatum SB010

Annotation: YfcC family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 505 signal peptide" amino acids 1 to 30 (30 residues), see Phobius details transmembrane" amino acids 122 to 145 (24 residues), see Phobius details amino acids 158 to 177 (20 residues), see Phobius details amino acids 184 to 207 (24 residues), see Phobius details amino acids 215 to 235 (21 residues), see Phobius details amino acids 241 to 261 (21 residues), see Phobius details amino acids 302 to 323 (22 residues), see Phobius details amino acids 329 to 346 (18 residues), see Phobius details amino acids 354 to 374 (21 residues), see Phobius details amino acids 401 to 435 (35 residues), see Phobius details amino acids 453 to 474 (22 residues), see Phobius details amino acids 480 to 502 (23 residues), see Phobius details PF03606: DcuC" amino acids 11 to 503 (493 residues), 419.9 bits, see alignment E=1.2e-129 PF03600: CitMHS" amino acids 120 to 378 (259 residues), 43.5 bits, see alignment E=2.4e-15

Best Hits

Swiss-Prot: 53% identical to Y594_HAEIN: Uncharacterized protein HI_0594 (HI_0594) from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

KEGG orthology group: None (inferred from 97% identity to fnu:FN2106)

Predicted SEED Role

"Arginine/ornithine antiporter ArcD" in subsystem Arginine Deiminase Pathway or Arginine and Ornithine Degradation or Polyamine Metabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (505 amino acids)

>HUW76_00105 YfcC family protein (Fusobacterium nucleatum SB010)
MSTNKKKKRGFPSAFTVLAIILVLAAALTYIVPSGQFSRLTYDDSTNEFVITDHDNNVTT
EPATQEVLDRLQIQLSLNKFTEGVIKKPIAIPGTYQRIEQRPQGFLDIIKAPVTGSMDTV
DIMLFVLVLGGIIGIINKIGAFDAGMAALSKRTKGKEFLLVTLVFLLTTLGGTTFGLAEE
TIAFYPILMPIFLLSGFDVLTCIAAIYMGSSIGTMFSTVNPFATVIASNAAGISFTEGLT
FRIITLILASIITLAYMYWYAQKVKKDKTKSYVYVDEEEIHRRFLGEYDSNTEKEFTWRR
KLCLLIFALAFPVLIWGVSLGGWWFEEMTALFLGVAVVIMFLSGLSEKEAINTFIAGAGD
LVGVVLTIGLARSINIVMDNGFISDTLLYYSTEFVAGMSKGTFAVAQLIIFSFLGFFIPS
SSGLAVLSMPIMAPLADTVGLSREVVINAYNWGQGWMSFITPTGLILVTLEMAGTTFDKW
LKYILPLMGIMGVFSVLMLIINTML