Protein Info for HMPREF1181_RS16805 in Bacteroides stercoris CC31F

Annotation: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 206 PF02527: GidB" amino acids 15 to 185 (171 residues), 121.5 bits, see alignment E=2.8e-39 TIGR00138: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG" amino acids 21 to 204 (184 residues), 121.7 bits, see alignment E=1.4e-39 PF13847: Methyltransf_31" amino acids 62 to 149 (88 residues), 44.2 bits, see alignment E=1.7e-15

Best Hits

Swiss-Prot: 87% identical to RSMG_BACTN: Ribosomal RNA small subunit methyltransferase G (rsmG) from Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482)

KEGG orthology group: K03501, ribosomal RNA small subunit methyltransferase G [EC: 2.1.1.170] (inferred from 86% identity to bhl:Bache_2608)

Predicted SEED Role

"rRNA small subunit 7-methylguanosine (m7G) methyltransferase GidB"

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.1.1.170

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (206 amino acids)

>HMPREF1181_RS16805 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG (Bacteroides stercoris CC31F)
MELILKYFPDLTEEQKRQFAALYDLYTDWNSKINVISRKDIENLYEHHVLHSLGIAKVIR
FKPGTKVMDLGTGGGFPGIPLAILFPEVQFHLVDSIGKKVRVATEIAGSIGLKNVTTRHA
RAEEEKQLFDFVVSRAVMPLTDLLKIIRKNISPKQQNALPNGLICLKGGELERETMPVKN
KTTMWNLKEFFGEEFFETKKVVYVAN