Protein Info for HMPREF1181_RS16520 in Bacteroides stercoris CC31F

Annotation: pyruvate, phosphate dikinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 906 TIGR01828: pyruvate, phosphate dikinase" amino acids 3 to 904 (902 residues), 1336.9 bits, see alignment E=0 PF01326: PPDK_N" amino acids 22 to 390 (369 residues), 250 bits, see alignment E=5.9e-78 PF00391: PEP-utilizers" amino acids 456 to 537 (82 residues), 74.7 bits, see alignment E=5.5e-25 PF02896: PEP-utilizers_C" amino acids 552 to 902 (351 residues), 274.7 bits, see alignment E=1.4e-85

Best Hits

KEGG orthology group: K01006, pyruvate,orthophosphate dikinase [EC: 2.7.9.1] (inferred from 96% identity to bhl:Bache_2550)

Predicted SEED Role

"Pyruvate,phosphate dikinase (EC 2.7.9.1)" in subsystem Glycolysis and Gluconeogenesis or Glycolysis and Gluconeogenesis, including Archaeal enzymes or Pyruvate metabolism I: anaplerotic reactions, PEP (EC 2.7.9.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.9.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (906 amino acids)

>HMPREF1181_RS16520 pyruvate, phosphate dikinase (Bacteroides stercoris CC31F)
MDKKRVYTFGNGQAEGKAGMRNLLGGKGANLAEMNLIGVPVPPGFTITTEVCTEYYEMGQ
EKVVALLKQEVENAIAHVETLMRSKFGDVENPLLVSVRSGARASMPGMMDTILNLGLNDE
VVEGLIRKTGNPRFAWDSYRRFVQMYGDVVLGMKPVNKEDVDPFEAIIEEVKHAKGVKLD
NELEVEDLKELVKRFKAAVKQQTGKDFPTCAYEQLWGAVCAVFNSWMNERAILYRKMEGI
PDEWGTAVSVQAMVFGNMGDTSATGVCFSRDAATGEDLFNGEYLINAQGEDVVAGIRTPQ
QITIIGSRRWAELAGVSEEERAAKYPSMEEAMPEIYKELDALQTKLENHYKDMQDMEFTV
QEGKLWFLQTRNGKRTGAAMVKIAMDLLHQGMIDEKTALLRCEPNKLDELLHPVFDKAAL
KQAKVLTRGLPASPGAACGQIVFFADDAAEWHAAGKRVVMVRIETSPEDLAGMAVAEGIL
TARGGMTSHAAVVARGMGKCCVSGAGALNIDYKARTVEVDGVVLKEGDFISLNGSTGEVY
KGKVETKAAELSGDFAELMQLADKYTKLQVRTNADTPHDAQVARNFGAVGIGLCRTEHMF
FEGEKIKAMREMILAENAEGRRKALSKILPYQQADFKGIFKAMEGCPVTVRLLDPPLHEF
VPHDLKGQQEMADTMGVSLQYIQQRVEALCEHNPMLGHRGCRLGNTYPEITQMQTRAILG
AALELKKEGVETHPEIMVPLTGILYEFKQQEEVIRAEAAKLFAEAGDSIEFKVGTMIEIP
RAALTADRIASSAEFFSFGTNDLTQMTFGYSRDDIASFLPIYLEKKILKVDPFQVLDQNG
VGQLVRMATEKGRAIRPDLKCGICGEHGGEPSSVKFCHKVGLNYVSCSPFRVPIARLAAA
QAAIEE