Protein Info for HMPREF1181_RS15490 in Bacteroides stercoris CC31F

Annotation: anaerobic ribonucleoside-triphosphate reductase activating protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 166 TIGR02491: anaerobic ribonucleoside-triphosphate reductase activating protein" amino acids 4 to 148 (145 residues), 162.2 bits, see alignment E=4.5e-52 PF13353: Fer4_12" amino acids 13 to 146 (134 residues), 141.5 bits, see alignment E=2.2e-45 PF04055: Radical_SAM" amino acids 25 to 116 (92 residues), 47.7 bits, see alignment E=2.1e-16

Best Hits

KEGG orthology group: K04068, anaerobic ribonucleoside-triphosphate reductase activating protein [EC: 1.97.1.4] (inferred from 87% identity to bhl:Bache_2028)

Predicted SEED Role

"Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4)" in subsystem Ribonucleotide reduction (EC 1.97.1.4)

Isozymes

Compare fitness of predicted isozymes for: 1.97.1.4

Use Curated BLAST to search for 1.97.1.4

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (166 amino acids)

>HMPREF1181_RS15490 anaerobic ribonucleoside-triphosphate reductase activating protein (Bacteroides stercoris CC31F)
MLSILDIIEDTTVDGPGFRTAIYAAGCPNGCPGCHNPESWDINRGRWMSTDEILQKVLAD
SFADVTFSGGDPMYQPEGFTELAHAIKRQSRKNIWCYTGYTFETLLHNPRQAKLLEYIDV
LVDGKFKEELRDEDLYFRGSSNQRLIDVQASLKAQKAVDYVYNPKL