Protein Info for HMPREF1181_RS15240 in Bacteroides stercoris CC31F

Annotation: PD-(D/E)XK nuclease family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 963 PF12705: PDDEXK_1" amino acids 669 to 962 (294 residues), 135 bits, see alignment E=2.4e-43

Best Hits

KEGG orthology group: None (inferred from 77% identity to bfr:BF2134)

Predicted SEED Role

"FIG00403299: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (963 amino acids)

>HMPREF1181_RS15240 PD-(D/E)XK nuclease family protein (Bacteroides stercoris CC31F)
MKTFLQSVAQDLYSKIGNDLSRTAIVFPNKRASLFFNEYLAAQSDRPLWSPAYVNISELF
RSLSPLKPGDPIRLVCELYKVFREETHSEEPLDDFYFWGELLISDFDDADKNLVDADKLF
SNLQDLKNIMDDYDFLDQEQEEAIQQFFQNFSIDKRTQLKEKFISLWDKLGDIYRHYRKN
LSELGIAYEGMMYRHVIEELDTDRLRYDRYVFVGFNVLNKVETHFFQRLQDAGKAMFYWD
YDVFYTRLPHEQQPPYVHEAGEFILRNLKLFPNQLPETAFDVLRHPKKIRFISAPTENAQ
ARYLPQWVRTVVKSDTEASKEKENAIVLCNEALLLPVLHSIPPEVENVNITMGFPLAQTP
VYSYINALMELQTTGYRRDTGRYTYEAALAVLKHPYTRQLSATAEDLEKQLTKDNRFYPL
PSELKKDAFLEQVFTPQNGTAAICRYLTELLREVAVIYRQEKDEEDIFNQLYRESLFKGY
TLINRLLSLIENDGLSLHTDTLKRLMNRLLTATNIPFHGEPAIGMQVMGVLETRNLDFRN
LIMLSLNEGQLPKAGGDSSFIPYNLRKAFGMTTIEHKNSVYAYYFYRLIQRAENITLLYN
TASDGLNRGEMSRFMLQFLVESPHDISRQYLEAGQSPQQSLKIEIHKTDEVLQRMYNAYD
IRRHPNALFSPSALNTYLDCRLRFYYRYVAGLKAPDEVSAEIDSALFGTIFHRSAELVYQ
DLTANGKEIRREDLEQLLRNDVRLQAYVDTAFKEEFFHVPAGEQPEYNGTQLIHSKVIAS
YLRQLLRNDLQYAPFRMEGMEQKVTETLEIETPSGMLPLNIGGTIDRMDSKGDTLRIVDY
KTGGTPKTPESIEQLFTPADNRPNYIFQTFLYAAIMCRKQGLKVAPSLLYIHRAASESYS
PVIEMGAPRQPKVPVNNFAFYEDEFRERLSALLQEIYNPEEPFTQTEDAKKCEYCDFKRL
CKK