Protein Info for HMPREF1181_RS14835 in Bacteroides stercoris CC31F

Annotation: phosphatidylinositol-4-phosphate 5-kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 385 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details PF02493: MORN" amino acids 51 to 73 (23 residues), 11.9 bits, see alignment (E = 9e-06) amino acids 74 to 94 (21 residues), 31.3 bits, see alignment (E = 6e-12) amino acids 97 to 119 (23 residues), 21.9 bits, see alignment (E = 6.1e-09) amino acids 120 to 141 (22 residues), 17.2 bits, see alignment (E = 1.9e-07) amino acids 143 to 164 (22 residues), 31.8 bits, see alignment (E = 4.4e-12) amino acids 166 to 187 (22 residues), 27.5 bits, see alignment (E = 1e-10) amino acids 189 to 210 (22 residues), 31.3 bits, see alignment (E = 6.3e-12) amino acids 212 to 234 (23 residues), 22.4 bits, see alignment (E = 4.1e-09) amino acids 235 to 256 (22 residues), 16.7 bits, see alignment (E = 2.7e-07) amino acids 258 to 279 (22 residues), 30.7 bits, see alignment (E = 1e-11) amino acids 281 to 302 (22 residues), 27.9 bits, see alignment (E = 7.6e-11) amino acids 304 to 325 (22 residues), 27.1 bits, see alignment (E = 1.3e-10) amino acids 327 to 349 (23 residues), 16.1 bits, see alignment (E = 4.2e-07) amino acids 350 to 362 (13 residues), 8.3 bits, see alignment (E = 0.00013)

Best Hits

KEGG orthology group: None (inferred from 84% identity to bhl:Bache_2440)

Predicted SEED Role

"FIG01057005: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (385 amino acids)

>HMPREF1181_RS14835 phosphatidylinositol-4-phosphate 5-kinase (Bacteroides stercoris CC31F)
MKYLYTAIFLLYLSQGSVAAQEKGGFFDKIKGTFSSEIKIGTHTFKDGSVYTGEMKGRKP
NGKGKTVFKNGDVYEGEYVKGKREGYGIYTFPDGEKYDGQWFQDQQHGRGIYYFMNNNRY
DGMWYQDYQHGKGTMYYYNGDLYEGDWINDKREGQGTYVWKNGSKYIGSWKDDKKNGEGT
LVWNDGCKYDGQWKNDVRDGKGTFEYANGDKYVGDWKEDMQHGKGIYFFHTGDRYEGSYV
QGERTGEGIYYHASGNKYVGNFKNGMQDGHGTFTWANGAVYDGQWKDNQRNGYGVYKWNV
GDSYEGEWKDNKFNGQGTLILTDGTKYKGGFVNGLEEGSGVQEDKNGNRYEGFFKQGKKD
GPFVETDKNGKLVRKGTYKMGRLSN