Protein Info for HMPREF1181_RS14570 in Bacteroides stercoris CC31F

Annotation: NAD(P)H-dependent oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 185 transmembrane" amino acids 54 to 74 (21 residues), see Phobius details PF02525: Flavodoxin_2" amino acids 7 to 169 (163 residues), 116 bits, see alignment E=2e-37 PF03358: FMN_red" amino acids 46 to 113 (68 residues), 25 bits, see alignment E=1.2e-09

Best Hits

Swiss-Prot: 37% identical to GS14_BACSU: General stress protein 14 (ywrO) from Bacillus subtilis (strain 168)

KEGG orthology group: K00358, [EC: 1.6.99.-] (inferred from 69% identity to bth:BT_0673)

Predicted SEED Role

"NAD(P)H oxidoreductase YRKL (EC 1.6.99.-) @ Putative NADPH-quinone reductase (modulator of drug activity B) @ Flavodoxin 2" (EC 1.6.99.-)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.6.99.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (185 amino acids)

>HMPREF1181_RS14570 NAD(P)H-dependent oxidoreductase (Bacteroides stercoris CC31F)
MDKGIKQVVILLAHPDIKSSQANKALMDAVKEMEEVAIYNLYEMRPEDSYNIDLWSKIIS
QASALVFQFPLYWMSAPSLLKKWQDEVFTYLAKTPAVAGKALLVAVTTGSEYSAYRSGGR
NNFTMDELLRPYQASALHAGMVWQTPVVAYGMGTADAGKNIAEGVNDYKLKIESLIGKSH
VSGDW