Protein Info for HMPREF1181_RS14560 in Bacteroides stercoris CC31F

Annotation: rhomboid family intramembrane serine protease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 771 transmembrane" amino acids 355 to 378 (24 residues), see Phobius details amino acids 406 to 426 (21 residues), see Phobius details amino acids 437 to 455 (19 residues), see Phobius details amino acids 461 to 481 (21 residues), see Phobius details amino acids 493 to 511 (19 residues), see Phobius details amino acids 517 to 535 (19 residues), see Phobius details amino acids 547 to 566 (20 residues), see Phobius details PF05076: SUFU" amino acids 156 to 313 (158 residues), 93.4 bits, see alignment E=1.5e-30 PF01694: Rhomboid" amino acids 395 to 534 (140 residues), 109 bits, see alignment E=2.3e-35

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (771 amino acids)

>HMPREF1181_RS14560 rhomboid family intramembrane serine protease (Bacteroides stercoris CC31F)
MATGFRPKYERTIELAGYSAEELMLLAIEASKSLGWQAGSIKRDKSDFYTPTSFRSWQEK
VILSVTDGKDGQLLATSICTSMQFMDWGKNKQNLNKLTATMQQLQNVHNISPTEADTANK
TTCAYTPEEKNTVISHIRHFYGGIKGITKNIVSPSGVEILIVEPTSRFDCYTLVTCGAGA
SVMPVPDKATPSRCEFCMCMPPTWNTEDSWPIDWLLQCVSWLQQGDSWLACGHSLSDGTP
LQDDTLMTSMLLTIPEERDKGAENCQLPNGDSVAIYQLVPVYTEEVLFKQANGIIPLLDK
MKNVSYIVDTHRENTCRNFSAFEENGDSSISMDEKANASLRSILTIRKGNMATPLLVYIN
IALFVVMSICGVNLLAPTGISIIKWGADFGPLTLTGDWWRTITCNFIHIGVIHVLMNMYA
LLYIGIFLEQLIGGRRLISAYFLTGLFSALASLTMHPETISAGASGSIFGLYGIFLSYLV
FHHRIEKGQRKSLLYSIGFFVFYNLMSGARAEGIDNAAHIGGLVSGIILGIIYLLTDRFA
TKKTSTLFISITEISFVLIFTVLFAGQTSNLPVDFIEIREMWENGTLEEYAQSVSSEKDT
IETDPNTSYYMPQNATDVSTFTGSETDLGNGMKEYINNSCGFSCQYPSTWETIGKSDTEQ
ILQLRGHGVSSLTVSYIKAPSKGAMEHMYDLLINSMKESRSENINIHGKTFERISGKMEC
AVAGGGSIHINQNIVIHMNEETLENFIITSTTSDDSSESEVQEIIKTIRIN