Protein Info for HMPREF1181_RS13950 in Bacteroides stercoris CC31F

Annotation: MATE family efflux transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 448 transmembrane" amino acids 12 to 30 (19 residues), see Phobius details amino acids 49 to 77 (29 residues), see Phobius details amino acids 96 to 121 (26 residues), see Phobius details amino acids 133 to 153 (21 residues), see Phobius details amino acids 166 to 188 (23 residues), see Phobius details amino acids 194 to 214 (21 residues), see Phobius details amino acids 237 to 259 (23 residues), see Phobius details amino acids 265 to 285 (21 residues), see Phobius details amino acids 319 to 343 (25 residues), see Phobius details amino acids 358 to 376 (19 residues), see Phobius details amino acids 397 to 416 (20 residues), see Phobius details amino acids 422 to 439 (18 residues), see Phobius details PF01554: MatE" amino acids 22 to 181 (160 residues), 100.3 bits, see alignment E=9.4e-33 amino acids 244 to 404 (161 residues), 59 bits, see alignment E=4.9e-20 TIGR00797: MATE efflux family protein" amino acids 22 to 405 (384 residues), 167.1 bits, see alignment E=2.8e-53 PF14667: Polysacc_synt_C" amino acids 137 to 257 (121 residues), 47.9 bits, see alignment E=1.5e-16

Best Hits

KEGG orthology group: None (inferred from 88% identity to bhl:Bache_1554)

Predicted SEED Role

"conserved hypothetical protein, putative membrane protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (448 amino acids)

>HMPREF1181_RS13950 MATE family efflux transporter (Bacteroides stercoris CC31F)
MATSREMTEGRALPLIFNFTLPLLLGNLLQQTYSLVDAAIVGKFLGINALASVGASTSVI
FLILGFCNGCCGGFGIPVAQKFGARDYITMRRYVAVSLQLAAVMSVVLAVVTSICCADIL
RMMRTPDNIFTGAYYYLLVTFIGVPCTFFYNLLSSIIRALGDSKTPFWFLLFSTVLNILL
DLFCILVLDWGVAGAAVATVFSQGVSAVLCYIYMMKRFEILRTTPAERKFDSALARTLMY
IGVPMGLQFSITAIGSIMLQSANNALGTACVAAFTAAMRIKMFFMCPFESLGMAMATYSG
QNYGAGKPGRIWQGVKASALMMIVYWAFTFAVLMVGAKTFTLLFVEASEVEILKDAELFL
HISVSFFPILGLLCILRYTIQGVGYTNLAMLSGVSEMIARILISLLAVPAFGYIAVCFGD
PTAWIFADLFLIPAFVYVYRRILRMNKN