Protein Info for HMPREF1181_RS13660 in Bacteroides stercoris CC31F

Annotation: toll/interleukin-1 receptor domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 PF01582: TIR" amino acids 99 to 173 (75 residues), 29.8 bits, see alignment E=7.7e-11 PF13676: TIR_2" amino acids 99 to 186 (88 residues), 53.7 bits, see alignment E=4.5e-18

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (350 amino acids)

>HMPREF1181_RS13660 toll/interleukin-1 receptor domain-containing protein (Bacteroides stercoris CC31F)
MFEIIYNETFERKYSNKQPSFVFYFGNLNHSEKDIDILKVLLDNGDAILPIYFGDNFEAE
VPKIIHVMNGRQYIADHIEKYINYAFESMRLLRENRKLFISYRRTDSSAVANQLFDAFVR
NNYDVFLDTYSINPAKNFQEELHHRMTDCDVLIQLYTNDFKNSKWCNEEIISANQKQIGV
VEIIWPDCTPDIHNLLCEPIQLTQKMFMNEDFHNGSCCITEECIENIVNAVESVRARNLA
ARQDNLVGEFVEEARKQGRQLIQEYRYLVETLKDDIIRLFIPAIGIPQSYDCFDSLRFRK
LLDNEKIELFLIYDDLRIRKKWVEHLEWLNESLEVKTIKKKDFELWLKNN