Protein Info for HMPREF1181_RS13645 in Bacteroides stercoris CC31F

Annotation: DEAD/DEAH box helicase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 901 transmembrane" amino acids 177 to 195 (19 residues), see Phobius details PF04313: HSDR_N" amino acids 47 to 118 (72 residues), 31.3 bits, see alignment E=5.9e-11 PF04851: ResIII" amino acids 152 to 336 (185 residues), 120.9 bits, see alignment E=1.5e-38 PF00270: DEAD" amino acids 157 to 341 (185 residues), 37.1 bits, see alignment E=8e-13 PF18766: SWI2_SNF2" amino acids 158 to 373 (216 residues), 79.4 bits, see alignment E=1e-25 PF08463: EcoEI_R_C" amino acids 720 to 892 (173 residues), 100.2 bits, see alignment E=4.4e-32

Best Hits

KEGG orthology group: K01153, type I restriction enzyme, R subunit [EC: 3.1.21.3] (inferred from 90% identity to bth:BT_4517)

Predicted SEED Role

"Type I restriction-modification system, restriction subunit R (EC 3.1.21.3)" in subsystem Restriction-Modification System (EC 3.1.21.3)

Isozymes

Compare fitness of predicted isozymes for: 3.1.21.3

Use Curated BLAST to search for 3.1.21.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (901 amino acids)

>HMPREF1181_RS13645 DEAD/DEAH box helicase family protein (Bacteroides stercoris CC31F)
MTPEEKARIKIDQWFADAGWEVVDREDYEPTCTAVAIREGLLKGNLEADYFLFINGKAVG
ILEAKREETDAFASKVCDQATLYARSVPNIYQAYQKPLPFIFTSNGKELYFCDFREQDSY
FRQIMAIPTPHELVKKLGIEDTFAGLPTLKKKGLRDCQYEAVTELEKSFRSGRNRALMVL
ATGAGKTYTACLATYRMLSYTPMRRVLFLVDRNNLGKQAEGEFGTFRLTENGDAFNTIFT
VNRLRSSSIPSDSNVVISTIQRLFSFLKGDIIEDNEEDDGNEPMEEVILPPNPNLPHDYF
DMIIIDECHRSIYGNWRKVLEYFDTARLVGLTATPIEETEKFFNYNIIVNYTLEKSIVDG
VNVDCRVYRIKTQVTESGGAILEGEKFKEETKYTGEVKTKNSKETKFYTNKELNRSIINP
AQIKLILSTYRDVVYTELFNDPQREPNIDYLPKTLIFALNETHATNIVQIAKEVFGRTDD
RFVQKITYSAGDSNELIRQFRNDKDFRIAVTCTLVATGTDVKPLEVVMFMRDVESLPLYI
QMKGRGVRTIGDEQLRNVTPNAFSKDCFYLVDAVGVTESMKTVKPIDGSPTTKTITLKEL
LERISHGYIPDEYLKRLAATLARIYYKADESQKKEFARLSHHDMKELSAKIYAVLEKGTL
PPFVSTDDSNNERKGLVSPLANHADARRYLLILAAGFVNTLMPGEDALISKGFSVEEAKD
TTEAFEDFCKKYYDEIEALRIIHSNTGEPITYSMLKDLENKLKMANNHFSPKQIWNSYAI
LSPNKVKHSTTKEESDALTNIIQLVRFAFRQIERLDSVVTTSKQYFNLWLGQTQREITDK
QCEVVSRIVDYIASNGACTVRDIREDDATHAAQMIRAFGNMQKADEALHSLYKFVVLRNA
A